A Dose Ranging Study To Investigate The Efficacy And Safety Of SB-742457 In Alzheimer's Disease
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|ClinicalTrials.gov Identifier: NCT00224497|
Recruitment Status : Completed
First Posted : September 23, 2005
Last Update Posted : December 24, 2009
|Condition or disease||Intervention/treatment||Phase|
|Alzheimer's Disease||Drug: SB-742457||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||380 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||A Phase IIa/b Double-blind, Randomised, Placebo-controlled, Linear Trend Design Dose-ranging Study to Investigate the Effects of 24 Weeks of Monotherapy With SB-742457 on Cognition in Subjects With Mild to Moderate Alzheimer's Disease|
|Study Start Date :||September 2005|
- Change in cognition and function after 24 weeks.
- Change in behavioural symptoms, activities of daily living and caregiver burden after 24 weeks. Changes in all symptoms at 8 and 12 weeks. Safety and tolerability. PK and dose response profiling. Efficacy related to ApoE status.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00224497
Show 48 Study Locations
|Study Director:||GSK Clinical Trials, MD||GlaxoSmithKline|