Role of Left Ventricular Pacing Site
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00221780|
Recruitment Status : Unknown
Verified June 2007 by University Hospital, Bordeaux.
Recruitment status was: Recruiting
First Posted : September 22, 2005
Last Update Posted : June 29, 2007
|Condition or disease||Intervention/treatment||Phase|
|Heart Failure Cardiomyopathy, Dilated Coronary Disease||Device: left ventricular pacing||Not Applicable|
Background. Cardiac resynchronization therapy has been shown to be effective in reducing symptoms and mortality in heart failure patients. However, very few is known about the importance of the left ventricular pacing site.
Design. Single-blind, monocentric, randomized cross-over study comparing 11 left ventricular pacing sites in a random order.
Intervention. Left ventricular DDD pacing on 11 ventricular sites, prior to the implantation. At each pacing site, a control hemodynamics will be obtained in AAI pacing at the same pacing rate. At each pacing site, 2 AV delays, a short and a long one, will be assessed.
Eligibility criteria. Patients referred for cardiac resynchronization therapy for heart failure
Outcomes. Hemodynamic measures using pressure-volume catheters.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||33 participants|
|Intervention Model:||Crossover Assignment|
|Official Title:||Importance of Left Ventricular Pacing Site in Biventricular Resynchronization Therapy for Severe Heart Failure|
|Study Start Date :||November 2003|
|Estimated Study Completion Date :||December 2007|
- Variation in left ventricular dp/dt max
- pressures and volumes of the left ventricle
- stroke work
- surface ECG repolarisation
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00221780
|Contact: Pierre Jaïs, Dr||33 (0) 5 57 65 64 firstname.lastname@example.org|
|Hôpital Cardiologique du Haut Lévêque, Rythmology department, Pr CLEMENTY, 3rd Floor||Recruiting|
|Pessac, France, 33604|
|Contact: Pierre Jaïs, Dr 33 (0) 5 57 65 64 71 email@example.com|
|Principal Investigator: Pierre Jaïs, Dr|
|Principal Investigator:||Pierre Jaïs, Dr||University Hospital, Bordeaux|
|Study Chair:||Paul Perez, Dr||University Hospital, Bordeaux|