REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION IN the Treatment of DEPRESSION
Recruitment status was: Recruiting
Subjects received rTMS daily on 10 consecutive weekdays (five sessions per week), during 20 minutes per session.During the rTMS session, the coil was centered flat over the right parietal cortex.
We follow the patient during 12 weeks after the 2 weeks of tms (follow-up period) to measure the depression with different rating scales.
We hypothesized that rTMS has a positive effect in the treatment of depression
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Official Title:||Right Parietal Inhibition With rTMS in the Treatment of Depression|
- To determine the depression (and so the effect of the treatment)we use the 10-item Montgomery Asberg Depression Rating Scale (MADRS)and we measure before tms (T=0), at week 1 (T=1), at week 2 (T=2), at week 4 (T=3), at week 8 (T=4), at week 14 (T=5)
- Besides the MADRS we use the BDI (Beck depression Inventory, the Hamillton deppression and anxiety scale)
- -Changes in anxiety
- -.Autonomic changes
- -.changes in the emotioneal attention, in the emotional memory en in de emotional recognition.
- -.Biochemical changes
- -.Changes in the EEG
- >> measured before tms and after (at T=0 and T=2)
|Study Start Date:||May 2004|
|Estimated Study Completion Date:||December 2006|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00220610
|st. Lucas Andreas Ziekenhuis/ Hospital|
|Amsterdam, Netherlands, 1061 AE|
|Study Director:||G.F Koerselman, prof. dr.||st Lucas Andreas Ziekenhuis|