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Chylothorax Following Heart Surgery

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ClinicalTrials.gov Identifier: NCT00215098
Recruitment Status : Terminated (insufficient data)
First Posted : September 22, 2005
Last Update Posted : March 16, 2012
Sponsor:
Information provided by:
Children's Healthcare of Atlanta

Brief Summary:
The purpose of this study is to determine at risk populations for certain congenital heart defects or certain operative procedures and to define the associated morbidity secondary to chylothorax - prolonged chest tube drainage, prolonged hospital stay, need for central access and hyperalimentation, subsequent infection.

Condition or disease
Chylothorax

Detailed Description:

Chylothorax is not uncommon following congenital heart surgery. It often results in prolonged chest tube drainage and hospital stays. Due to the feeding difficulties, it often results in malnutrition and the need for central hyperalimentation. In addition, it results in a depressed immune system with the possibility of subsequent infection. Chylothorax can be a significant contributor to post-operative morbidity and mortality.

The primary aims are to determine at risk populations - certain congenital heart defects or certain operative procedures, to define the associated morbidity secondary to chylothorax - prolonged chest tube drainage, prolonged hospital stay, need for central access and hyperalimentation, subsequent infection and to review our current treatment methods - change formulas, hyperalimentation, somatostatin. The secondary aims are to determine ways to prevent chylothorax, determine the most successful treatment method, and to discover better treatment methods. This study will be conducted through a retrospective chart review.


Study Type : Observational
Estimated Enrollment : 70 participants
Time Perspective: Retrospective
Official Title: Chylothorax in Children Following Congenital Heart Surgery
Study Start Date : May 2005
Actual Study Completion Date : November 2006




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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients in the congenital surgery database
Criteria

Inclusion Criteria:

  • Patients in the congenital surgery database
  • patients have developed post-operative chylous effusions

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00215098


Locations
United States, Georgia
Children's Healthcare of Atlanta at Egleston
Atlanta, Georgia, United States, 30322
Sponsors and Collaborators
Children's Healthcare of Atlanta
Investigators
Principal Investigator: Brian Kogon, MD Emory University

ClinicalTrials.gov Identifier: NCT00215098     History of Changes
Other Study ID Numbers: 05-093
First Posted: September 22, 2005    Key Record Dates
Last Update Posted: March 16, 2012
Last Verified: June 2007

Keywords provided by Children's Healthcare of Atlanta:
pediatric health
cardiac
congenital heart surgery
post-operative chylous effusions
heart defects
children

Additional relevant MeSH terms:
Chylothorax
Pleural Diseases
Respiratory Tract Diseases