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Treatment of Subclinical Hyperthyroidism

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00213720
Recruitment Status : Terminated (recruitment difficulties)
First Posted : September 21, 2005
Last Update Posted : September 29, 2020
Sponsor:
Information provided by (Responsible Party):
University Hospital, Strasbourg, France

Brief Summary:
Objective: To determine if the treatment of subclinical hyperthyroidism will reduce the rate of atrial fibrillation, the main complication of this condition.

Condition or disease
Subclinical Hyperthyroidism Atrial Fibrillation

Detailed Description:
Randomized open-labelled multicentre study comparing radioiodine vs medical supervision without treatment

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Study Type : Observational
Actual Enrollment : 145 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Place de l'Iode RadioActif Dans l'HyperThyroïdiE Sub-clinique (PIRHATES)/ Evaluation of the Interest of Subclinical Hyperthyroidism Treatment
Study Start Date : August 2005
Actual Primary Completion Date : November 2019
Actual Study Completion Date : January 2020

Resource links provided by the National Library of Medicine





Biospecimen Retention:   Samples Without DNA
serum


Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patients referred to tertiary hospitals for advice on thyroïd disease
Criteria

Inclusion Criteria:

  • Men and women aged 50 and greater
  • Isolated decreased thyroid-stimulating hormone (TSH) with normal FT4 and FT3 levels

Exclusion Criteria:

  • Iodide overload
  • Non sinusal heart rhythm
  • Severe heart disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00213720


Locations
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Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
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Principal Investigator: Bernard Goichot, MD Hopitaux Universitaires de Strasbourg
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Responsible Party: University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier: NCT00213720    
Other Study ID Numbers: 3463
First Posted: September 21, 2005    Key Record Dates
Last Update Posted: September 29, 2020
Last Verified: August 2019
Keywords provided by University Hospital, Strasbourg, France:
Hyperthyroidism
atrial fibrillation
quality of life
radioiodine treatment
Additional relevant MeSH terms:
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Atrial Fibrillation
Hyperthyroidism
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes
Thyroid Diseases
Endocrine System Diseases