myoARRAY and TcLandscape Analysis for the Diagnosis of Inflammatory Myopathies (MYOARRAY)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00213629|
Recruitment Status : Completed
First Posted : September 21, 2005
Last Update Posted : February 16, 2012
The diagnosis of the different forms of inflammatory myopathies (polymyositis, dermatomyositis, inclusion-body myositis...) remains difficult which may lead to unappropriate patient care.
Objective 1 : to develop and evaluate the diagnostic value of a dedicated DNA-array (myoARRAY) for adult-onset muscular diseases with focus on inflammatory myopathies.
Objective 2 : to evaluate the diagnostic value of T cell repertoire (TcLand) analysis to distinguish different forms of inflammatory myopathies.
|Condition or disease||Intervention/treatment||Phase|
|Polymyositis Dermatomyositis||Other: transcriptome analysis Other: T cell repertoire analysis||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||100 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Transcriptome Analysis Through a Dedicated Macro-array and TcLandscape Repertoire Analysis for Diagnosis of Myositis.|
|Study Start Date :||November 2004|
|Actual Primary Completion Date :||July 2010|
|Actual Study Completion Date :||July 2010|
Other: transcriptome analysis
transcriptome analysis from muscle biopsy
Other: T cell repertoire analysis
blood T cell repertoire analysis
- transcriptome [ Time Frame: at inclusion ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00213629
|University Hospital of Rouen|
|Rouen, Seine Maritime, France, 76000|
|Principal Investigator:||Olivier Boyer, MD, PhD||University Hospital, Rouen|