Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-year Manometric Follow-up
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|ClinicalTrials.gov Identifier: NCT00213460|
Recruitment Status : Completed
First Posted : September 21, 2005
Last Update Posted : April 16, 2013
Small bowel involvement is still recognized to be associated with great morbidity and mortality in SSc patients, leading particularly to malabsorption and intestinal pseudo-obstruction. Intestinal disorders directly related to SSc have, in fact, been reported to be one of the most common causes of death.
In a previous prospective study, we have demonstrated the high prevalence of small intestinal involvement in SSc patients, using upper intestinal manometry; in turn, 88% of our SSc patients had upper intestinal motor disturbances. However, to date, no authors have yet analyzed the course of upper intestinal motor dysfunction in SSc.
The aims of this study were therefore to assess the 5-year course of small bowel motor disorders, using manometry in patients with systemic sclerosis (SSc), and to investigate for an association between upper intestinal motor dysfunction outcome and other clinical manifestations of SSc.
|Condition or disease|
|Study Type :||Observational|
|Official Title:||Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-year Manometric Follow-up|
|Study Start Date :||August 2001|
|Actual Study Completion Date :||July 2003|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00213460
|Rouen, Rouen Cedex, France, 76031|
|Principal Investigator:||Isabelle MARIE, MD, PhD||CHU Rouen|