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Cerebral Resonance Magnetic Imaging During Rectal Distention

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ClinicalTrials.gov Identifier: NCT00213330
Recruitment Status : Withdrawn (patients with inflammatory colitis not included)
First Posted : September 21, 2005
Last Update Posted : April 23, 2012
Sponsor:
Information provided by (Responsible Party):
University Hospital, Rouen

Brief Summary:
Irritable bowel syndrome is responsible for chronic abdominal pain, diarrhea and/or constipation. It is a very frequent problem. However, the exact cause of irritable bowel syndrome remains unknown. The purpose of this study is to look for a different cerebral response by magnetic resonance imaging after rectal stimulation in patients with irritable bowel syndrome compared to healthy subjects and to patients with digestive organic disease. Our hypothesis is that irritable bowel syndrome could be a problem of cerebral integration of visceral stimulation.

Condition or disease Intervention/treatment
Ulcerative Colitis Irritable Bowel Syndrome Procedure: rectal distension

Study Type : Observational
Actual Enrollment : 0 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Cerebral Activity During Rectal Pain in Patients With Irritable Bowel Syndrome or Inflammatory Bowel Disease:Resonance Magnetic Imaging Study.
Study Start Date : April 2003
Study Completion Date : February 2006

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
healthy subjects and patients with irritable bowel syndrome
Criteria

Inclusion Criteria:

  • healthy subjects irritable bowel syndrome (Rome II criteria) colitis ulcerative

Exclusion Criteria:

pregnant or breast feeding metallic material implanted good tolerance of rectal distension acute phase of ulcerative colitis


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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00213330


Locations
France
University hospital of Rouen
Rouen, France, 76031
Sponsors and Collaborators
University Hospital, Rouen
Investigators
Principal Investigator: Emmanuel Gérardin, MD University Hospital, Rouen

Responsible Party: University Hospital, Rouen
ClinicalTrials.gov Identifier: NCT00213330     History of Changes
Other Study ID Numbers: 2001/105/HP
First Posted: September 21, 2005    Key Record Dates
Last Update Posted: April 23, 2012
Last Verified: April 2012

Keywords provided by University Hospital, Rouen:
cerebral activity
rectal distension
colitis ulcerative
irritable bowel syndrome
magnetic resonance imaging

Additional relevant MeSH terms:
Colitis
Ulcer
Colitis, Ulcerative
Syndrome
Irritable Bowel Syndrome
Disease
Pathologic Processes
Gastroenteritis
Gastrointestinal Diseases
Digestive System Diseases
Colonic Diseases
Intestinal Diseases
Inflammatory Bowel Diseases
Colonic Diseases, Functional