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Cerebral Resonance Magnetic Imaging During Rectal Distention

This study has been withdrawn prior to enrollment.
(patients with inflammatory colitis not included)
ClinicalTrials.gov Identifier:
First Posted: September 21, 2005
Last Update Posted: April 23, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
University Hospital, Rouen
Irritable bowel syndrome is responsible for chronic abdominal pain, diarrhea and/or constipation. It is a very frequent problem. However, the exact cause of irritable bowel syndrome remains unknown. The purpose of this study is to look for a different cerebral response by magnetic resonance imaging after rectal stimulation in patients with irritable bowel syndrome compared to healthy subjects and to patients with digestive organic disease. Our hypothesis is that irritable bowel syndrome could be a problem of cerebral integration of visceral stimulation.

Condition Intervention
Ulcerative Colitis Irritable Bowel Syndrome Procedure: rectal distension

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Cerebral Activity During Rectal Pain in Patients With Irritable Bowel Syndrome or Inflammatory Bowel Disease:Resonance Magnetic Imaging Study.

Resource links provided by NLM:

Further study details as provided by University Hospital, Rouen:

Enrollment: 0
Study Start Date: April 2003
Estimated Study Completion Date: February 2006

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
healthy subjects and patients with irritable bowel syndrome

Inclusion Criteria:

  • healthy subjects irritable bowel syndrome (Rome II criteria) colitis ulcerative

Exclusion Criteria:

pregnant or breast feeding metallic material implanted good tolerance of rectal distension acute phase of ulcerative colitis

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00213330

University hospital of Rouen
Rouen, France, 76031
Sponsors and Collaborators
University Hospital, Rouen
Principal Investigator: Emmanuel Gérardin, MD University Hospital, Rouen
  More Information

Responsible Party: University Hospital, Rouen
ClinicalTrials.gov Identifier: NCT00213330     History of Changes
Other Study ID Numbers: 2001/105/HP
First Submitted: September 13, 2005
First Posted: September 21, 2005
Last Update Posted: April 23, 2012
Last Verified: April 2012

Keywords provided by University Hospital, Rouen:
cerebral activity
rectal distension
colitis ulcerative
irritable bowel syndrome
magnetic resonance imaging

Additional relevant MeSH terms:
Colitis, Ulcerative
Irritable Bowel Syndrome
Pathologic Processes
Gastrointestinal Diseases
Digestive System Diseases
Colonic Diseases
Intestinal Diseases
Inflammatory Bowel Diseases
Colonic Diseases, Functional