Single Dose Versus Multiple Doses of Dexamethasone in Children With Acute Bronchiolitis
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This study is to determine the effectiveness of five-day treatment versus a single dose of oral dexamethasone (corticosteroid) in children between 2 and 24 months of age with a first episode of acute bronchiolitis presenting in the Emergency Department
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Layout table for eligibility information
Ages Eligible for Study:
2 Months to 24 Months (Child)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
infants 2 to 24 months of age
acute bronchiolitis, defined as first episode of wheezing with upper respiratory infection and respiratory distress
moderate to severe baseline disease severity (Respiratory Distress Index (RDAI) score 6 to 15)
only patients discharged at or shortly after 240 minutes of uniform stabilization therapy will be randomized