Effects of Hormonal Contraceptives on Liver Proteins and Coagulation Factors: A Comparison of a Contraceptive Vaginal Ring and an Oral Contraceptive
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|ClinicalTrials.gov Identifier: NCT00213096|
Recruitment Status : Completed
First Posted : September 21, 2005
Last Update Posted : August 14, 2017
|Condition or disease||Intervention/treatment||Phase|
|Contraception||Drug: Nestorone/ethinyl estradiol contraceptive vaginal ring; levonorgestrel/ethinyl estradiol oral contraceptive||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||50 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||A Randomized, Open-Label Study Comparing the Effect of a Contraceptive Vaginal Ring Delivering Daily Doses of 150 Micrograms Nestorone and 15 Micrograms Ethinyl Estradiol to an Oral Contraceptive Containing 150 Micrograms of Levonorgestrel and 30 Micrograms of Ethinyl Estradiol Per Tablet on Hepatic Factors Including Coagulation Factors|
|Actual Study Start Date :||March 2003|
|Actual Study Completion Date :||February 2004|
- Comparison of the differences between contraceptive vaginal ring and oral contraceptive treatment groups in change from baseline to end of treatment in serum angiotensinogen and sex-hormone binding globulin.
- Comparison of the differences between contraceptive vaginal ring & oral contraceptive treatment groups in change from baseline to end of treatment in serum or plasma concentrations of 15 other hepatic proteins, coagulation factors & coagulation markers.
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00213096
|Center for Human Drug Research|
|Principal Investigator:||Regine Sitruk-Ware, MD||Population Council|