Optimal Multimodal Analgesia in Laparoscopic Cholecystectomy
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00209885 |
Recruitment Status : Unknown
Verified September 2005 by Hvidovre University Hospital.
Recruitment status was: Not yet recruiting
First Posted : September 21, 2005
Last Update Posted : September 21, 2005
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Cholecystolithiasis | Drug: Gabapentin Drug: S-ketamine Drug: Lidocaine Drug: Droperidol | Phase 4 |
Aim of the study: to compare postoperative complaints (PONV, pain, etc) and PACU discharge time between two groups:
- A: standard of care (SOC)receiving intraoperative dexamethasone, ondansetron, ketorolac, and general anaesthesia with propofol, remifentanil and cisatracurium
- B: SOC + preoperative gabapentin, intraoperative lidocain infusion, s-ketamin and droperidol.
Primary endpoints:
- postoperative abilities over time
- discharge time from PACU according to fixed criteria
- consumption of analgesics and antiemetics in the PACU
Secondary endpoints:
- degree of nursing requirements at the PACU
- General tolerability of the regimes
Study Type : | Interventional (Clinical Trial) |
Enrollment : | 60 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double |
Primary Purpose: | Treatment |
Study Start Date : | October 2005 |
- 1. postoperative abilities over time in PACU
- 2. discharge time from PACU according to fixed criteria
- 3. consumption of analgesics and antiemetics in the PACU
- 1. Degree of nursing requirements in the PACU
- 2. General tolerability of the regimens

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Elective laparoscopic cholecystectomy
- Age above 18 years
- Written informed consent
- ASA class I-III
Exclusion Criteria:
- Planned abdominal cholecystectomy
- Intraoperative conversion of laparoscopic to laparotomic cholecystectomy
- Allergy to part of the treatment regimens
- Previous reactions to opioids (nausea, cognition)

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00209885
Contact: Kenneth Jensen, M.D. | +45 36 32 62 90 | kenneth.jensen@hh.hosp.dk |
Denmark | |
Dept of Anaesthesia, Hvidovre Hospital | |
Copenhagen, Hvidovre, Denmark, 2650 | |
Contact: Kenneth Jensen, M.D. +45 36 32 62 90 kenneth.jensen@hh.hosp.dk | |
Principal Investigator: Kenneth Jensen, M.D. |
Principal Investigator: | Kenneth Jensen, M.D. | Dept of Anaesthesia, Acute Pain Service, Hvidovre Hospital, Copenhagen, Denmark | |
Study Chair: | Claus Lund, dr.med.sci | Dept of Anaesthesia, Hvidovre Hospital, Copenhagen, Denmark |
ClinicalTrials.gov Identifier: | NCT00209885 |
Other Study ID Numbers: |
OMA-LC01 |
First Posted: | September 21, 2005 Key Record Dates |
Last Update Posted: | September 21, 2005 |
Last Verified: | September 2005 |
Cholecystolithiasis Cholelithiasis Gallstones Biliary Tract Diseases Digestive System Diseases Gallbladder Diseases Calculi Pathological Conditions, Anatomical Lidocaine Droperidol Ketamine Gabapentin Esketamine Anesthetics, Local Anesthetics |
Central Nervous System Depressants Physiological Effects of Drugs Sensory System Agents Peripheral Nervous System Agents Anti-Arrhythmia Agents Voltage-Gated Sodium Channel Blockers Sodium Channel Blockers Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action Analgesics Anesthetics, Dissociative Anesthetics, Intravenous Anesthetics, General Excitatory Amino Acid Antagonists Excitatory Amino Acid Agents |