Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting

This study has been completed.
Information provided by:
Centers for Disease Control and Prevention
ClinicalTrials.gov Identifier:
First received: September 13, 2005
Last updated: NA
Last verified: September 2005
History: No changes posted
This study was designed to determine whether taking daily doxycycline during an outbreak of Mycoplasma pneumoniae could prevent a person from getting infected and interrupt ongoing disease transmission during an outbreak. Doxycycline is a treatment for Mycoplasma pneumoniae, but it is not certain that the drug could prevent disease if used prophylactically.

Condition Intervention
Mycoplasma Pneumoniae
Drug: Doxycycline treatment

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double-Blind
Official Title: A Double-Blind, Randomized Placebo-Controlled Trial of Doxycycline for Chemoprophylaxis in the Setting of an Outbreak of Mycoplasma Pneumoniae

Resource links provided by NLM:

Further study details as provided by Centers for Disease Control and Prevention:

Study Start Date: January 1994
Estimated Study Completion Date: April 1994

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

- Working at hospital facility where outbreak of Mycoplasma pneumoniae occured

Exclusion Criteria:

- Pregnant, on antiseizure medications, allergic to macrolide antibiotics

  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00207584

Sponsors and Collaborators
Centers for Disease Control and Prevention
Principal Investigator: Julia A Schillinger, MD Centers for Disease Control and Prevention
  More Information

ClinicalTrials.gov Identifier: NCT00207584     History of Changes
Other Study ID Numbers: CDC-NCHSTP-9997 
Study First Received: September 13, 2005
Last Updated: September 13, 2005
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Mycoplasma Infections
Pneumonia, Mycoplasma
Bacterial Infections
Gram-Negative Bacterial Infections
Lung Diseases
Mycoplasmatales Infections
Pleural Diseases
Pneumonia, Bacterial
Respiratory Tract Diseases
Respiratory Tract Infections
Anti-Bacterial Agents
Anti-Infective Agents
Antiparasitic Agents
Antiprotozoal Agents

ClinicalTrials.gov processed this record on May 24, 2016