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Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00207584
First Posted: September 21, 2005
Last Update Posted: September 21, 2005
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Centers for Disease Control and Prevention
  Purpose
This study was designed to determine whether taking daily doxycycline during an outbreak of Mycoplasma pneumoniae could prevent a person from getting infected and interrupt ongoing disease transmission during an outbreak. Doxycycline is a treatment for Mycoplasma pneumoniae, but it is not certain that the drug could prevent disease if used prophylactically.

Condition Intervention
Mycoplasma Pneumoniae Drug: Doxycycline treatment

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Official Title: A Double-Blind, Randomized Placebo-Controlled Trial of Doxycycline for Chemoprophylaxis in the Setting of an Outbreak of Mycoplasma Pneumoniae

Resource links provided by NLM:


Further study details as provided by Centers for Disease Control and Prevention:

Study Start Date: January 1994
Estimated Study Completion Date: April 1994
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

- Working at hospital facility where outbreak of Mycoplasma pneumoniae occured

Exclusion Criteria:

- Pregnant, on antiseizure medications, allergic to macrolide antibiotics

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00207584


Sponsors and Collaborators
Centers for Disease Control and Prevention
Investigators
Principal Investigator: Julia A Schillinger, MD Centers for Disease Control and Prevention
  More Information

ClinicalTrials.gov Identifier: NCT00207584     History of Changes
Other Study ID Numbers: CDC-NCHSTP-9997
First Submitted: September 13, 2005
First Posted: September 21, 2005
Last Update Posted: September 21, 2005
Last Verified: September 2005

Additional relevant MeSH terms:
Pneumonia
Pleuropneumonia
Mycoplasma Infections
Pneumonia, Mycoplasma
Lung Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Pleurisy
Pleural Diseases
Mycoplasmatales Infections
Gram-Negative Bacterial Infections
Bacterial Infections
Pneumonia, Bacterial
Doxycycline
Anti-Bacterial Agents
Anti-Infective Agents
Antimalarials
Antiprotozoal Agents
Antiparasitic Agents