Neurosurgical Use of Interstitial Laser Therapy (ILT) (ILT)
Recruitment status was: Recruiting
The researchers' specific aims are to test the following hypotheses:
Hypothesis 1: A tumor can be completely ablated by ILT with MRI-guidance.
Hypothesis 2: The MRI-based 3D temperature map of tissue during ILT is predictive of destruction.
Hypothesis 3: The 3D "thermal dose" map that is based on the tissue's temperature over time is more predictive of tissue destruction than the temperature map.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Neurosurgical Use of Interstitial Laser Therapy (ILT)|
- Ablation of lesion [ Time Frame: During procedure ]
- Patients undergoing ILT will be assessed pre- and post-operatively based on a neurological exam by a physician and patient self-assessment using the Glioma Outcomes Questionnaire [ Time Frame: 3 Months ]
|Study Start Date:||January 2002|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
Neurosurgical use of Interstitial Laser therapy
Device: Interstitial Laser Therapy
Other Name: ILT
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00207350
|United States, Massachusetts|
|Brigham & Women's Hospital|
|Boston, Massachusetts, United States, 02155|
|Principal Investigator:||Ferenc Jolesz, MD||Brigham and Women's Hospital|