Surveillance For New Lung Primaries

This study has been terminated.
(low accrual)
Information provided by (Responsible Party):
University of Wisconsin, Madison Identifier:
First received: September 13, 2005
Last updated: July 9, 2015
Last verified: July 2015
The primary goal of this study is to determine the prevalence of tracheobronchial carcinomas in patients with a history of squamous cell cancer of the aerodigestive tract who have been treated with a curative intent and remain disease free. Detection of pre-invasive and invasive lesions (moderate to severe dysplasia, CIS) with fluorescence bronchoscopic surveillance may help to define the natural history of these lesions and allow earlier intervention should they progress to invasive lesions.

Lung Cancer

Study Type: Observational
Study Design: Observational Model: Cohort
Official Title: Fluorescence Bronchoscopic Surveillance For New Lung Primaries After Curative Therapy for Squamous Cell Carcinoma of the Aerodigestive Tract"

Resource links provided by NLM:

Further study details as provided by University of Wisconsin, Madison:

Estimated Enrollment: 200
Study Start Date: December 2001
Study Completion Date: December 2005
Primary Completion Date: December 2005 (Final data collection date for primary outcome measure)
Fluorescence bronchosopy with sputum cytology
Patients undergo surgery with Fluorescence bronchosopy and sputum cytology.


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Study Population
Patients with new lung primaries after curative therapy for squamous cell carcinoma of the aerodigestive tract

Inclusion Criteria:

  • History squamous cell NSCLC who have undergone complete resection or definitive chemotherapy

Exclusion Criteria:

  • History of an aerodigestive tract carcinoma of non-squamous histology
  • Patients who have Stage IIIA, IIIB or IV squamous cell lung cancer that have undergone resection or chemotherapy within three years
  • Patients who have Stage I or II squamous cell lung cancer that have undergone resection or chemotherapy within one year
  • Patients who have received external beam radiation therapy for treatment of a squamous cell cancer of the lung
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00205439

United States, Wisconsin
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States, 53792
Sponsors and Collaborators
University of Wisconsin, Madison
Principal Investigator: Tracey Weigel, MD University of Wisconsin Medical School
  More Information

No publications provided

Responsible Party: University of Wisconsin, Madison Identifier: NCT00205439     History of Changes
Other Study ID Numbers: 2001-431
Study First Received: September 13, 2005
Last Updated: July 9, 2015
Health Authority: United States: Institutional Review Board processed this record on November 27, 2015