Haloperidol vs. Risperidone in the Treatment of Aggression in Psychotic Inmates

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00203775
Recruitment Status : Terminated
First Posted : September 20, 2005
Last Update Posted : October 13, 2006
Janssen Pharmaceutica N.V., Belgium
Information provided by:
UConn Health

Brief Summary:
This study examines the efficacy of haldol versus risperdal in the treatment of aggression in psychotic prison inmates. It is hypothsized that risperdal will be more effective in decreasing aggression than haldol.

Condition or disease Intervention/treatment Phase
Psychosis Aggression Drug: risperidone Not Applicable

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Efficacy of Risperidone Versus Haloperidol in the Treatment of Aggression and Hostility in Psychotic Inmates
Study Start Date : July 2002
Study Completion Date : April 2004

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:age 18 or over, psychotic disorder diagnosed on SCID, inmate at correctional facility for at least 2 weeks -

Exclusion Criteria: active withdrawal from substances of abuse, non-psychotic individuals, pregnant women, people unable to give informed consent, patients on mood stabilizers

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00203775

United States, Connecticut
University of connecticut health center
Farmington, Connecticut, United States, 06030
Sponsors and Collaborators
University of Connecticut
Janssen Pharmaceutica N.V., Belgium
Principal Investigator: catherine f lewis, md UConn Health Identifier: NCT00203775     History of Changes
Other Study ID Numbers: RIS-USA-269
IRB Project Number 01-250
First Posted: September 20, 2005    Key Record Dates
Last Update Posted: October 13, 2006
Last Verified: May 2005

Additional relevant MeSH terms:
Behavioral Symptoms
Haloperidol decanoate
Serotonin Antagonists
Serotonin Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Antipsychotic Agents
Tranquilizing Agents
Central Nervous System Depressants
Psychotropic Drugs
Dopamine Antagonists
Dopamine Agents
Autonomic Agents
Peripheral Nervous System Agents
Gastrointestinal Agents
Anti-Dyskinesia Agents