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Multiple Sclerosis Rehabilitation Study

This study has been completed.
Information provided by:
Melbourne Health Identifier:
First received: September 12, 2005
Last updated: June 1, 2015
Last verified: June 2015
The effects of routine rehabilitation in MS patients versus no rehabilitation.

Condition Intervention
Multiple Sclerosis
Behavioral: Physiotherapy
Behavioral: Occupational therapy
Behavioral: Speech pathology

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: 'Functioning and Disability' and 'Quality of Life' in an Australian Community Cohort With Multiple Sclerosis.

Resource links provided by NLM:

Further study details as provided by Melbourne Health:

Primary Outcome Measures:
  • Improvement in fatigue levels and psychological well being (depression, stress and anxiety) in MS patients. Outcome will be measured at 13 months since recruitment.

Secondary Outcome Measures:
  • - Improvement in function and activities of daily living ie. disability- Quality of life.- Carer Burder in multiple sclerosis.- Utilisation of health services.- 13 months follow up.

Estimated Enrollment: 100
Study Start Date: December 2004
Study Completion Date: December 2005
Primary Completion Date: December 2005 (Final data collection date for primary outcome measure)
Detailed Description:
Routine rehabilitation inervention in patients with MS. This comprises of medical and nursing input, physiotherapy, occupational therapy, speech pathology, neuropsychology, compared with a "control" group on the waiting list for rehabilitation intervention. Duration of intervention is 6 weeks.

Ages Eligible for Study:   19 Years to 64 Years   (Adult)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Confirmed diagnosis of MS (Paty)- Community dwelling participants with known neurological and psychological deficits per EDSS groups.- Age 19-64 years.- Male and female participants.- Residing within 60kms of metropolitan Melbourne.- Have mobility problem.- Adequate cognition (KFS=2).

Exclusion Criteria:

  • Patients residing in nursing home and other residential care.- Those with severe cognitive problems KFS>2.-
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00202254

Sponsors and Collaborators
Melbourne Health
Principal Investigator: Fary Khan Melbourne Extended Care Rehabilitation Service
  More Information Identifier: NCT00202254     History of Changes
Other Study ID Numbers: HREC 2004.101  MelbUni HREC 040334 
Study First Received: September 12, 2005
Last Updated: June 1, 2015
Health Authority: Australia: Human Research Ethics Committee

Keywords provided by Melbourne Health:
Mulitple Sclerosis

Additional relevant MeSH terms:
Multiple Sclerosis
Pathologic Processes
Demyelinating Autoimmune Diseases, CNS
Autoimmune Diseases of the Nervous System
Nervous System Diseases
Demyelinating Diseases
Autoimmune Diseases
Immune System Diseases processed this record on October 20, 2016