Effects of Variable Ventilation on Respiratory System of Acute Respiratory Distress Syndrome (ARDS) Patients
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00202098|
Recruitment Status : Completed
First Posted : September 20, 2005
Last Update Posted : March 19, 2015
|Condition or disease||Intervention/treatment||Phase|
|ARDS||Procedure: Variable ventilation||Not Applicable|
In this interventional study we want to evaluate the effect of Variable ventilation (1) in patients with ARDS. Patients will be mechanically ventilated with Variable Ventilation (3 step with increased level of variability) and "traditional" CMV, for a total of 4 step. Each step lasts in 60 minutes. During this period we will record the gas exchange parameters and the mechanics of the respiratory system.
1. Arold S, Mora R, Lutchen K, et al. Variable ventilation improves lung mechanics and gas exchange in a rodent model of acute lung injury. Am J Resp Crit Care Med 2000; 165: 366-71.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||16 participants|
|Intervention Model:||Single Group Assignment|
|Official Title:||Effects of Variable Ventilation on Respiratory System of ARDS Patients|
|Study Start Date :||March 2005|
|Actual Primary Completion Date :||March 2013|
|Actual Study Completion Date :||March 2015|
Procedure: Variable ventilation
Patients will be mechanically ventilated with Variable Ventilation (3 step with increased level of variability) and "traditional" CMV, for a total of 4 step. Each step lasts in 60 minutes. During this period the investigators will record the gas exchange parameters and the mechanics of the respiratory system.
- Gas exchange and respiratory mechanics [ Time Frame: within the first 60 minutes from the ventilatory change ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00202098
|Principal Investigator:||Paolo Taccone, MD||Policlinico Hospital, milan|