Asthma, a Disease Due to a Lack of Bacterial Infections in Childhood.
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|ClinicalTrials.gov Identifier: NCT00200928|
Recruitment Status : Completed
First Posted : September 20, 2005
Last Update Posted : April 4, 2006
|Condition or disease||Intervention/treatment||Phase|
|Food Allergy Atopic Dermatitis Asthma Rhinitis||Biological: BCG||Not Applicable|
A randomised single blinded intervention study in high-risk newborns vaccinated at the age of 6 weeks with BCG or placebo.
Inclusion: high-risk was defined as either a mother or a father and a sibling with present or past atopic disease.
Exclusion: maternal infection in the last week of pregnancy, the use of immunomodulatory drugs or antibiotics during pregnancy (mother), the use of antibiotics directly post-partum (newborn)
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||120 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Asthma, a Disease Due to a Lack of Bacterial Infections in Childhood.|
|Study Start Date :||January 1999|
|Study Completion Date :||July 2005|
- Incidence and severity of atopic disease.
- SCORAD, lung function, IgE, cytokine production by PBMNC's, NRAMP-polymorphisms.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00200928
|Wilhelmina Children's Hospital (UMCU)|
|Utrecht, Netherlands, 3508AB|
|Principal Investigator:||Maarten O Hoekstra, MD PhD||Wilhelmina Children's Hospital Utrecht (UMCU)|