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Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2005 by University Hospital, Limoges.
Recruitment status was  Recruiting
Information provided by:
University Hospital, Limoges Identifier:
First received: September 14, 2005
Last updated: March 10, 2006
Last verified: September 2005

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus.

The investigators recently proved that incompatibility between mother and child can concern an organ leading to a tissular alloimmunization. For example, neonatal membranous glomerulonephritis (a kidney disease) can result from this mechanism.

The purpose of this network is to detect and study neonatal diseases induced by tissular fetomaternal alloimmunization. The detection of these diseases will be performed by the mother's serum analysis.

Glomerulonephritis, Membranous
Neonatal Diseases and Abnormalities

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

Resource links provided by NLM:

Further study details as provided by University Hospital, Limoges:

Estimated Enrollment: 100
Study Start Date: September 2005

Ages Eligible for Study:   Child, Adult, Senior
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

Mothers having a child suffering from:

  • Neonatal membranous glomerulonephritis
  • Unexplained neonatal tubular defect
  • Unexplained thrombotic microangiopathy
  • Neonatal hemochromatosis

Exclusion Criteria:

  • Any cause explaining the child's disease
  Contacts and Locations
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Please refer to this study by its identifier: NCT00199628

Contact: Vincent Guigonis, MD +33(0)555 056 358

Limoges University Hospital Recruiting
Limoges, France, 87042
Contact: Vincent Guigonis, MD    +33(0) 555 056 358   
Principal Investigator: Vincent Guigonis, MD         
Sponsors and Collaborators
University Hospital, Limoges
Principal Investigator: Vincent Guigonis, MD Department of Pediatrics, Limoges University Hospital
  More Information Identifier: NCT00199628     History of Changes
Other Study ID Numbers: I05001 
Study First Received: September 14, 2005
Last Updated: March 10, 2006
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Limoges:
fetomaternal tissular alloimmunization
Mothers having a child suffering from:
neonatal membranous glomerulonephritis
unexplained neonatal tubular defect
unexplained thrombotic microangiopathy
neonatal hemochromatosis

Additional relevant MeSH terms:
Infant, Newborn, Diseases
Glomerulonephritis, Membranous
Kidney Diseases
Urologic Diseases
Metal Metabolism, Inborn Errors
Metabolism, Inborn Errors
Genetic Diseases, Inborn
Iron Overload
Iron Metabolism Disorders
Metabolic Diseases
Autoimmune Diseases
Immune System Diseases processed this record on October 27, 2016