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Trial record 33 of 46 for:    "hemochromatosis"

Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

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ClinicalTrials.gov Identifier: NCT00199628
Recruitment Status : Completed
First Posted : September 20, 2005
Last Update Posted : January 15, 2019
Sponsor:
Information provided by (Responsible Party):
University Hospital, Limoges

Brief Summary:

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus.

The investigators recently proved that incompatibility between mother and child can concern an organ leading to a tissular alloimmunization. For example, neonatal membranous glomerulonephritis (a kidney disease) can result from this mechanism.

The purpose of this network is to detect and study neonatal diseases induced by tissular fetomaternal alloimmunization. The detection of these diseases will be performed by the mother's serum analysis.


Condition or disease
Glomerulonephritis, Membranous Neonatal Diseases and Abnormalities Hemochromatosis

Study Type : Observational
Actual Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization
Actual Study Start Date : September 2005
Actual Primary Completion Date : August 2013
Actual Study Completion Date : August 2014






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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   Female
Gender Based Eligibility:   Yes
Gender Eligibility Description:   pregnant woman
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
pregnant woman
Criteria

Inclusion Criteria:

Mothers having a child suffering from:

  • Neonatal membranous glomerulonephritis
  • Unexplained neonatal tubular defect
  • Unexplained thrombotic microangiopathy
  • Neonatal hemochromatosis

Exclusion Criteria:

  • Any cause explaining the child's disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00199628


Locations
France
Limoges University Hospital
Limoges, France, 87042
Sponsors and Collaborators
University Hospital, Limoges
Investigators
Principal Investigator: Vincent Guigonis, MD Department of Pediatrics, Limoges University Hospital

Responsible Party: University Hospital, Limoges
ClinicalTrials.gov Identifier: NCT00199628     History of Changes
Other Study ID Numbers: I05001
First Posted: September 20, 2005    Key Record Dates
Last Update Posted: January 15, 2019
Last Verified: September 2005

Keywords provided by University Hospital, Limoges:
fetomaternal tissular alloimmunization
Mothers having a child suffering from:
neonatal membranous glomerulonephritis
unexplained neonatal tubular defect
unexplained thrombotic microangiopathy
neonatal hemochromatosis

Additional relevant MeSH terms:
Hemochromatosis
Glomerulonephritis
Glomerulonephritis, Membranous
Infant, Newborn, Diseases
Nephritis
Kidney Diseases
Urologic Diseases
Metal Metabolism, Inborn Errors
Metabolism, Inborn Errors
Genetic Diseases, Inborn
Iron Overload
Iron Metabolism Disorders
Metabolic Diseases
Autoimmune Diseases
Immune System Diseases