Assessment of Prepulse Inhibition for Shock Pain Reduction
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00193986|
Recruitment Status : Completed
First Posted : September 19, 2005
Last Update Posted : November 14, 2006
Patient tolerance of pain from discharges of implantable cardioverter defibrillators (ICD's) is highly variable. It can be influenced by psychological factors, physical condition and the number of shocks delivered.
It has been shown that cutaneous pain perception can be reduced by delivery of a weak , low voltage pulse (prepulse)prior to the delivery of a stronger shock.
A prepulse delivered before a high voltage ICD shock will decrease discomfort compared to a shock of equal energy without a prepulse.
|Condition or disease||Intervention/treatment|
|Pain Awareness From ICD Shocks||Device: Arbitrary Waveform Defibrillator|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||10 participants|
|Intervention Model:||Crossover Assignment|
|Official Title:||Assessment of Prepulse Inhibition for Shock Pain Reduction- Ventricular|
|Study Start Date :||May 2005|
|Estimated Study Completion Date :||June 2005|
- Assessment from pain perception from a shock preceded by a prepulse compared to a non prepulsed shock
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00193986
|Toronto General Hospital|
|Toronto, Ontario, Canada, M5G 2C4|
|Principal Investigator:||Douglas A Cameron, MD||UHN|