Trial record 8 of 884 for:    Open Studies | "Mood Disorders"

The Serotonergic Transmitter System in Dementia and Affective Disorders

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2005 by Rigshospitalet, Denmark.
Recruitment status was  Recruiting
Information provided by:
Rigshospitalet, Denmark Identifier:
First received: September 13, 2005
Last updated: September 26, 2007
Last verified: September 2005
The aim of this project is to examine the serotonergic transmitter system using functional imaging of the brain (positron emission tomography [PET]) to gain knowledge about early pathophysiological changes in Alzheimer's dementia and mood disorders.

Mood Disorders
Alzheimer Disease

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Cross-Sectional

Resource links provided by NLM:

Further study details as provided by Rigshospitalet, Denmark:

Estimated Enrollment: 100
Study Start Date: October 2003

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Moderate to severe Alzheimer's disease
  • Individuals genetically predisposed to affective disorder
  • Healthy gender and age matched controls

Exclusion Criteria:

  • Contraindications to magnetic resonance imaging (MRI)
  • Use of psychoactive drugs
  • Past or present affective disorder
  • Other systemic diseases that may affect brain function
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00192998

Contact: Vibe G. Frokjaer, MD +45 3545 6714
Contact: Steen G. Hasselbalch, MD

Neurobiological Research Unit Recruiting
Copenhagen, Denmark, 2100
Contact: Vibe G. Frokjaer, MD    +45 3545 6714   
Principal Investigator: Vibe G. Frokjaer, MD         
Sponsors and Collaborators
Rigshospitalet, Denmark
Principal Investigator: Vibe G. Frokjaer, MD Neurobiological Research Unit, Copenhagen University Hospital, Denmark
  More Information

Additional Information: Identifier: NCT00192998     History of Changes
Other Study ID Numbers: SERT-AD 
Study First Received: September 13, 2005
Last Updated: September 26, 2007
Health Authority: Denmark: Ethics Committee

Keywords provided by Rigshospitalet, Denmark:
Affective disorder
Alzheimer dementia
healthy controls

Additional relevant MeSH terms:
Alzheimer Disease
Mood Disorders
Brain Diseases
Central Nervous System Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders
Nervous System Diseases
Neurodegenerative Diseases
Tauopathies processed this record on May 04, 2016