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Early Lung Cancer Detection Using Computed Tomography

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University Health Network, Toronto
ClinicalTrials.gov Identifier:
NCT00188734
First received: September 12, 2005
Last updated: August 9, 2016
Last verified: August 2016
  Purpose
Early detection of lung cancer may improve treatment outcomes. Risk factors have been identified, suggesting a population which might benefit from regular screening. Lung cancer screening using low-dose computed tomography (LDCT) has experienced a recent renaissance with reported sensitivity for detection of lung cancer of 2.7% in high-risk populations. The purpose of this study is to evaluate the utility of LCDT for the early diagnosis of lung cancer in Ontario.

Condition
Lung Cancer

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Lung Cancer Screening in High-risk Smokers Using Low-dose Computed Tomography

Resource links provided by NLM:


Further study details as provided by University Health Network, Toronto:

Enrollment: 5000
Study Start Date: September 2003
Study Completion Date: June 2016
Primary Completion Date: June 2016 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   55 Years to 85 Years   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
high risk current and former smokers
Criteria

Inclusion Criteria:

55 years or older at least 10 pack-year history of smoking general good health

Exclusion Criteria:

any prior cancers except non-melanotic skin cancer

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00188734

Locations
Canada, Ontario
Princess Margaret Hospital
Toronto, Ontario, Canada
Sponsors and Collaborators
University Health Network, Toronto
Investigators
Principal Investigator: Heidi C Roberts, MD University Health Network, Toronto
  More Information

Additional Information:
Responsible Party: University Health Network, Toronto
ClinicalTrials.gov Identifier: NCT00188734     History of Changes
Other Study ID Numbers: I-ELCAP 
Study First Received: September 12, 2005
Last Updated: August 9, 2016
Health Authority: Canada: Health Canada

Keywords provided by University Health Network, Toronto:
Lung Cancer
Eary Diagnosis
Screening

Additional relevant MeSH terms:
Lung Neoplasms
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Neoplasms
Lung Diseases
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on December 09, 2016