Magnetic Resonance (MR) in Asthmatic Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00188487
Recruitment Status : Suspended (no funding)
First Posted : September 16, 2005
Last Update Posted : April 23, 2007
Information provided by:
University Health Network, Toronto

Brief Summary:
Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.

Condition or disease Intervention/treatment Phase
Asthma Device: magnetic resonance imaging (MRI) of the thorax Phase 1

Detailed Description:
A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.

Study Type : Interventional  (Clinical Trial)
Enrollment : 80 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: MR Perfusion Imaging in Asthmatic Patients
Study Start Date : September 2005
Study Completion Date : December 2005

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Asthma

Primary Outcome Measures :
  1. The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests

Information from the National Library of Medicine

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Ages Eligible for Study:   16 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • All asthmatic patients are eligible.

Exclusion Criteria:

  • Patients in whom MRI is contraindicated

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00188487

Canada, Ontario
Toronto General Hospital
Toronto, Ontario, Canada
Sponsors and Collaborators
University Health Network, Toronto
Principal Investigator: Narinder Paul, FRCP C University Health Network, Toronto Identifier: NCT00188487     History of Changes
Other Study ID Numbers: 05-0174
First Posted: September 16, 2005    Key Record Dates
Last Update Posted: April 23, 2007
Last Verified: April 2007