This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Magnetic Resonance (MR) in Asthmatic Patients

This study has suspended participant recruitment.
(no funding)
Information provided by:
University Health Network, Toronto Identifier:
First received: September 12, 2005
Last updated: April 20, 2007
Last verified: April 2007
Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.

Condition Intervention Phase
Asthma Device: magnetic resonance imaging (MRI) of the thorax Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: MR Perfusion Imaging in Asthmatic Patients

Further study details as provided by University Health Network, Toronto:

Primary Outcome Measures:
  • The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests

Estimated Enrollment: 80
Study Start Date: September 2005
Estimated Study Completion Date: December 2005
Detailed Description:
A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.

Ages Eligible for Study:   16 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • All asthmatic patients are eligible.

Exclusion Criteria:

  • Patients in whom MRI is contraindicated
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00188487

Canada, Ontario
Toronto General Hospital
Toronto, Ontario, Canada
Sponsors and Collaborators
University Health Network, Toronto
Principal Investigator: Narinder Paul, FRCP C University Health Network, Toronto
  More Information Identifier: NCT00188487     History of Changes
Other Study ID Numbers: 05-0174
Study First Received: September 12, 2005
Last Updated: April 20, 2007 processed this record on August 22, 2017