Cardiopulmonary Bypass (CPB) Pumps and Blood Activation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00187967
Recruitment Status : Unknown
Verified September 2005 by University Hospital, Angers.
Recruitment status was:  Recruiting
First Posted : September 16, 2005
Last Update Posted : September 26, 2007
Information provided by:
University Hospital, Angers

Brief Summary:
Blood activation induced by cardiopulmonary bypass may compromise the postoperative outcome. The goal of this study is to compare blood activation induced by cardiopulmonary bypass performed with centrifugal pump or roller pump in patients undergoing coronary artery surgery.

Condition or disease Intervention/treatment Phase
Cardiopulmonary Bypass Coronary Artery Disease Device: pumps used for cardiopulmonary bypass Not Applicable

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Primary Purpose: Treatment
Official Title: Blood Activation During Cardiopulmonary Bypass Using Roller or Centrifugal Pumps
Study Start Date : January 2005

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   Male

Inclusion Criteria:

  • Men undergoing coronary artery bypass grafting using cardiopulmonary bypass
  • Aspirin therapy

Exclusion Criteria:

  • Redo surgery
  • Acute coronary syndrome requiring urgent surgery
  • Oral anticoagulant therapy
  • Organ dysfunction or chronic inflammatory disease
  • Surgery other than coronary artery bypass grafting

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00187967

Contact: Anthony Bailleul 33-(0)2-41-35-58-91

University Hospital of Angers Recruiting
Angers, France, 49933
Contact: Christophe Baufreton, MD, PhD    33-(0)2-41-35-45-73   
Contact: Anthony Bailleul    33-(0)2-41-35-58-91      
Sponsors and Collaborators
University Hospital, Angers
Principal Investigator: Christophe Baufreton, MD, PhD University Hospital of Angers, France Identifier: NCT00187967     History of Changes
Other Study ID Numbers: PHRC 03-03
First Posted: September 16, 2005    Key Record Dates
Last Update Posted: September 26, 2007
Last Verified: September 2005

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases