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Validation of Coregistered CT-PET Imaging in Determining Tumor Volume and Atelectasis in Patients With Operable Non-Small-Cell Lung Cancer and Tumor Associated Atelectasis

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ClinicalTrials.gov Identifier: NCT00184964
Recruitment Status : Unknown
Verified June 2008 by Radboud University.
Recruitment status was:  Recruiting
First Posted : September 16, 2005
Last Update Posted : June 4, 2008
Sponsor:
Information provided by:
Radboud University

Brief Summary:

CT-PET image fusion has the potential to differentiate 'tumor' from 'atelectasis' much better than the CT-scan in patients with non-small cell lung cancer who also have atelectasis.

This however has never been validated on a histological level. In this study patients with non small cell lung cancer and atelectasis who are eligible for surgery undergo a CT-scan and a PET-scan prior to surgery.

The resection specimen will be compared to the preoperative imaging.


Condition or disease Intervention/treatment
Carcinoma, Non Small Cell Lung Procedure: CT-scan, PET-scan

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 15 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: The Validation of Coregistered CT-PET Imaging in Determining Tumor Volume and Atelectasis in Patients With Operable Non-Small-Cell Lung Cancer and Tumor Associated Atelectasis With Histological Examination of the Resected Specimen
Study Start Date : June 2004

Resource links provided by the National Library of Medicine

U.S. FDA Resources




Primary Outcome Measures :
  1. Histological validation of CT-PET image fusion.


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

-Patients with non small cell lung cancer and atelectasis, who are eligible for surgery.

Exclusion Criteria:

  • age < 18 years
  • pregnancy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00184964


Contacts
Contact: Dominic A Schinagl, MD +31243614515 d.schinagl@rther.umcn.nl

Locations
Netherlands
Radboud University Nijmegen Medical Centre Recruiting
Nijmegen, Gelderland, Netherlands, 6500HB
Contact: Dominic A Schinagl, MD    +31243614515    d.schinagl@rther.umcn.nl   
Principal Investigator: Dominic A Schinagl, MD         
Sponsors and Collaborators
Radboud University
Investigators
Study Director: Jan Bussink, MD, PhD Radiation oncologist, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

ClinicalTrials.gov Identifier: NCT00184964     History of Changes
Other Study ID Numbers: 2004/032
First Posted: September 16, 2005    Key Record Dates
Last Update Posted: June 4, 2008
Last Verified: June 2008

Additional relevant MeSH terms:
Carcinoma, Non-Small-Cell Lung
Pulmonary Atelectasis
Carcinoma, Bronchogenic
Bronchial Neoplasms
Lung Neoplasms
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Neoplasms
Lung Diseases
Respiratory Tract Diseases