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Validation of Coregistered CT-PET Imaging in Determining Tumor Volume and Atelectasis in Patients With Operable Non-Small-Cell Lung Cancer and Tumor Associated Atelectasis

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2008 by Radboud University.
Recruitment status was:  Recruiting
Information provided by:
Radboud University Identifier:
First received: September 12, 2005
Last updated: June 3, 2008
Last verified: June 2008

CT-PET image fusion has the potential to differentiate 'tumor' from 'atelectasis' much better than the CT-scan in patients with non-small cell lung cancer who also have atelectasis.

This however has never been validated on a histological level. In this study patients with non small cell lung cancer and atelectasis who are eligible for surgery undergo a CT-scan and a PET-scan prior to surgery.

The resection specimen will be compared to the preoperative imaging.

Condition Intervention
Carcinoma, Non Small Cell Lung
Procedure: CT-scan, PET-scan

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: The Validation of Coregistered CT-PET Imaging in Determining Tumor Volume and Atelectasis in Patients With Operable Non-Small-Cell Lung Cancer and Tumor Associated Atelectasis With Histological Examination of the Resected Specimen

Resource links provided by NLM:

Further study details as provided by Radboud University:

Primary Outcome Measures:
  • Histological validation of CT-PET image fusion.

Estimated Enrollment: 15
Study Start Date: June 2004

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

-Patients with non small cell lung cancer and atelectasis, who are eligible for surgery.

Exclusion Criteria:

  • age < 18 years
  • pregnancy
  Contacts and Locations
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Please refer to this study by its identifier: NCT00184964

Contact: Dominic A Schinagl, MD +31243614515

Radboud University Nijmegen Medical Centre Recruiting
Nijmegen, Gelderland, Netherlands, 6500HB
Contact: Dominic A Schinagl, MD    +31243614515   
Principal Investigator: Dominic A Schinagl, MD         
Sponsors and Collaborators
Radboud University
Study Director: Jan Bussink, MD, PhD Radiation oncologist, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
  More Information Identifier: NCT00184964     History of Changes
Other Study ID Numbers: 2004/032
Study First Received: September 12, 2005
Last Updated: June 3, 2008

Additional relevant MeSH terms:
Carcinoma, Non-Small-Cell Lung
Pulmonary Atelectasis
Carcinoma, Bronchogenic
Bronchial Neoplasms
Lung Neoplasms
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Lung Diseases
Respiratory Tract Diseases processed this record on May 22, 2017