Now Available: Final Rule for FDAAA 801 and NIH Policy on Clinical Trial Reporting

Continued Early Intervention for Recent-Onset Schizophrenia

This study has been terminated.
The Research Council of Norway
Information provided by:
Norwegian University of Science and Technology Identifier:
First received: September 15, 2005
Last updated: NA
Last verified: September 2005
History: No changes posted
The purpose of this study was to determine whether outreach integrated treatment of first episode schizophrenia was more effecive than standard outpatient treatment.

Condition Intervention Phase
Behavioral: integrated psychosocial treatment (behavior)
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Continued Early Intervention for Recent-Onset Schizophrenia. A Randomized Controlled Study.

Resource links provided by NLM:

Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • Rehospitalizations and psychotic relapse at two years

Secondary Outcome Measures:
  • Psychopathology, psychosocial changes, functioning, antipsychotic medication

Estimated Enrollment: 50
Study Start Date: February 1993
Estimated Study Completion Date: May 1998
Detailed Description:

Early intervention for schizophrenia has spawned considerable enthusiasm among clinicians without solid research evidence to suport its benefits and costs. The present study is a random-controlled study of integrated biomedical and psychosocial treatment on a population of recent-onset cases.

Comparison(s): 50 consecutive referrals with schizophrenic disorders of less than two years duration were allocated randomly to a comprehensive model of integrated treatment or standard care for two years. Main outcome measures was psychopathology, psychosocial functioning and hospital admissions.


Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Genders Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • first-episode schizophrenia

Exclusion Criteria:

  • acute psychosis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00184509

Norwegian University of Science and Technology
Trondheim, Norway, N-7000
Sponsors and Collaborators
Norwegian University of Science and Technology
The Research Council of Norway
Study Director: K. Gunnar Gøtestam, MD Norwegian University of Science and Technology
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00184509     History of Changes
Other Study ID Numbers: SHDIR-1992-1995; NFR-1997-1999 
Study First Received: September 15, 2005
Last Updated: September 15, 2005
Health Authority: Norway: Norwegian Social Science Data Services

Keywords provided by Norwegian University of Science and Technology:
psychosocial treatment

Additional relevant MeSH terms:
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders processed this record on January 14, 2017