Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients

This study has been completed.
St. Olavs Hospital
Information provided by (Responsible Party):
Norwegian University of Science and Technology Identifier:
First received: September 15, 2005
Last updated: January 16, 2017
Last verified: November 2011

Maximal strength training has been shown to increase muscular strength, muscular volume and work economy. An 8 week maximal leg press training regime will be conducted on cardiac heart failure patients to evaluate whether they increase their maximal leg press strength, work economy, serum testosterone and quality of life. The study hypotheses are that:

  1. Aerobic work capacity will increase due to increased work economy, without increases in maximal oxygen uptake.
  2. Strength training will increase serum testosterone.

Condition Intervention
Heart Failure
Coronary Artery Disease
Behavioral: Strength training intervention

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Maximal Leg Press Strength Training for Coronary Artery Disease Patients. Training Effect on Serum Testosterone and Work Economy

Resource links provided by NLM:

Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • Maximal leg press strength
  • Work economy
  • Serum testosterone
  • Quality of life

Enrollment: 12
Study Start Date: September 2005
Study Completion Date: September 2007
Primary Completion Date: April 2007 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Clinically diagnosed coronary artery disease
  • Stable coronary artery disease
  • 1.5 mm depression in ST segment during a cycling strain test
  • Between 18-70 years of age

Exclusion Criteria:

  • Unstable coronary artery disease
  • Other limitations to exercise than coronary artery disease
  • Participants in other study interventions
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00184457

Norwegian University of Science and Technology
Trondheim, Norway, 7489
Sponsors and Collaborators
Norwegian University of Science and Technology
St. Olavs Hospital
Study Director: Asbjørn Støylen, MD Norwegian University of Science and Technology
  More Information

Responsible Party: Norwegian University of Science and Technology Identifier: NCT00184457     History of Changes
Other Study ID Numbers: 25060100
Study First Received: September 15, 2005
Last Updated: January 16, 2017

Keywords provided by Norwegian University of Science and Technology:
Cardiac heart failure
Leg press
Maximal strength training
Serum testosterone
Work economy

Additional relevant MeSH terms:
Heart Failure
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs processed this record on May 22, 2017