The Immune System and Psychiatric Disorders
|Study Design:||Observational Model: Cohort
Time Perspective: Cross-Sectional
|Official Title:||The Immune System and Psychiatric Disorders|
- cytokines [ Time Frame: 1 year ]
Biospecimen Retention: Samples Without DNA
|Study Start Date:||January 2005|
|Study Completion Date:||January 2008|
|Primary Completion Date:||January 2008 (Final data collection date for primary outcome measure)|
|All patients admitted to a psychiatric acute ward|
Our hypotheses are first that activity in the immune system influences the psychiatric status in general, second that changes in activity in psychiatric status affect activity in the immune system and third that there are connections between certain psychiatric conditions/disorders and certain features of the immune system.
All patients admitted to a psychiatric acute ward covering an area with a population of 130.000 and with around 1000 admittances to an acute psychiatric ward a year (some readmittances) are asked to participate in the study. Patients fill in a question form regarding psychiatric as well as somatic health with emphasis on diseases involving immune activity. When possible also slight information on the family is registered. Both at the time of admittance and after recovery clinical laboratory tests on somatic status are registered. In addition the level of different cytokines is measured. The psychiatric state and precise diagnoses are registered during the stay. The data will be analysed to uncover connections between psychiatric stress in general as well as specific psychiatric diagnoses and activity in the immune system.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00184418
|St Olavs Hospital, Department of Psychiatry, Østmarka Hospital|
|Trondheim, Middle Norway, Norway, N-7040|
|Study Chair:||Solveig K Reitan, MD, PhD||St Olavs Hospital/NTNU|