Understanding Treatment Adherence Among Individuals With Bipolar Disorder
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|ClinicalTrials.gov Identifier: NCT00183495|
Recruitment Status : Completed
First Posted : September 16, 2005
Last Update Posted : July 2, 2013
|Condition or disease|
Bipolar Disorder (BPD), also known as manic-depressive illness, is a disorder that causes frequent shifts in an individual's mood, energy, and ability to function. An individual with BPD may go through periods of mania, which are characterized by increased energy, irritability, and an excessively "high" euphoric mood. The manic periods are followed by periods of depression, which are characterized by decreased energy, feelings of hopelessness, and anxiety. BPD is a persistent and severe mental illness with a high suicide rate; it must be strictly managed through medication and therapy. Many BPD medications have been developed recently; however, there are still many individuals who do not respond well to medication treatment. Research has shown that the way individuals experience illness has an effect on their response to medication. The purpose of this study is to gain insight into how individuals with BPD perceive and respond to medication treatment. Factors such as gender, degree of social support, drug and alcohol usage, and attitudes towards medication will be evaluated to understand how they affect medication and treatment adherence.
This 6-month study will consist of 3 interviews. Each interview will last approximately 2 and ½ hours and will include numerous standardized psychological questionnaires. The questionnaires will assess participants' attitudes toward BPD treatment; psychiatric illness severity, including symptoms of mania and depression; level of addiction to alcohol and drugs; availability of social support resources; and medication adherence.
|Study Type :||Observational|
|Actual Enrollment :||140 participants|
|Official Title:||Determinants and Manifestation of Illness Behavior in Promoting Treatment Adherence Among Individuals With Bipolar Depression|
|Study Start Date :||March 2004|
|Actual Primary Completion Date :||March 2007|
|Actual Study Completion Date :||August 2007|
- Participants' attitudes toward BPD treatment; psychiatric illness severity, including symptoms of mania and depression; level of addiction to alcohol and drugs; availability of social support resources; and medication adherence [ Time Frame: Measured three times over 6 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00183495
|United States, Ohio|
|Northeast Ohio Health Services|
|Beachwood, Ohio, United States, 44122|
|Principal Investigator:||Martha Sajatovic, MD||Case Western Reserve University School of Medicine|