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Depression Prevention Program for Adolescents

This study has been completed.
National Institute of Mental Health (NIMH)
Information provided by (Responsible Party):
University of Texas at Austin Identifier:
First received: September 13, 2005
Last updated: April 23, 2012
Last verified: April 2012
This study will compare the effectiveness of two programs designed to prevent depression in adolescents.

Condition Intervention
Depression Behavioral: Cognitive behavior therapy (CBT) Behavioral: Supportive/expressive (S/E) therapy Behavioral: Bibliotherapy

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Depression Prevention Program for High-Risk Adolescents

Further study details as provided by University of Texas at Austin:

Primary Outcome Measures:
  • Depressive symptoms [ Time Frame: Measured at Year 1 ]

Enrollment: 350
Study Start Date: September 2004
Study Completion Date: May 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Participants will receive cognitive behavioral therapy
Behavioral: Cognitive behavior therapy (CBT)
Participants will complete worksheets and group discussion on how to increase positive mood and activity.
Active Comparator: 2
Participants will receive supportive/expressive therapy
Behavioral: Supportive/expressive (S/E) therapy
Participants will be encouraged to express feelings and emotions without advice giving.
Active Comparator: 3
Participants will receive bibliotherapy
Behavioral: Bibliotherapy
Participants will be given a book on how to increase their mood.
No Intervention: 4
Participants in the control condition will receive no treatment

Detailed Description:

Major depression is one of the most common psychiatric disorders in adolescents. In many cases, the condition is recurrent and can result in serious psychological impairment. A high number of depressed adolescents never receive treatment; therefore, it is crucial to develop prevention programs for this disorder that are effective and can be easily disseminated. This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT) and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents.

This study will last 2 years. Participants will be randomly assigned to receive six sessions of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention will focus on reducing negative thoughts and increasing engagement in pleasant activities. S/E therapy is designed to allow adolescents to express their negative emotions and talk about recent stressful events in a supportive environment of their peers. Surveys and psychiatric interviews will be completed by all participants and their parents at the beginning and the end of the study. The surveys and interviews will assess depressive symptoms.


Ages Eligible for Study:   14 Years to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Beck Depression Inventory score higher than 10
  • Parent or guardian willing to provide informed consent

Exclusion Criteria:

  • Diagnosis of depression
  Contacts and Locations
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Please refer to this study by its identifier: NCT00183417

United States, Texas
University of Texas at Austin
Austin, Texas, United States, 78712
Sponsors and Collaborators
University of Texas at Austin
National Institute of Mental Health (NIMH)
Principal Investigator: Eric M. Stice, PhD University of Texas at Austin
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: University of Texas at Austin Identifier: NCT00183417     History of Changes
Other Study ID Numbers: R01MH067183 ( U.S. NIH Grant/Contract )
Study First Received: September 13, 2005
Last Updated: April 23, 2012

Keywords provided by University of Texas at Austin:

Additional relevant MeSH terms:
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders processed this record on August 18, 2017