Depression Prevention Program for Adolescents
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|ClinicalTrials.gov Identifier: NCT00183417|
Recruitment Status : Completed
First Posted : September 16, 2005
Last Update Posted : April 25, 2012
|Condition or disease||Intervention/treatment||Phase|
|Depression||Behavioral: Cognitive behavior therapy (CBT) Behavioral: Supportive/expressive (S/E) therapy Behavioral: Bibliotherapy||Not Applicable|
Major depression is one of the most common psychiatric disorders in adolescents. In many cases, the condition is recurrent and can result in serious psychological impairment. A high number of depressed adolescents never receive treatment; therefore, it is crucial to develop prevention programs for this disorder that are effective and can be easily disseminated. This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT) and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents.
This study will last 2 years. Participants will be randomly assigned to receive six sessions of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention will focus on reducing negative thoughts and increasing engagement in pleasant activities. S/E therapy is designed to allow adolescents to express their negative emotions and talk about recent stressful events in a supportive environment of their peers. Surveys and psychiatric interviews will be completed by all participants and their parents at the beginning and the end of the study. The surveys and interviews will assess depressive symptoms.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||350 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Depression Prevention Program for High-Risk Adolescents|
|Study Start Date :||September 2004|
|Actual Primary Completion Date :||May 2009|
|Actual Study Completion Date :||May 2009|
Participants will receive cognitive behavioral therapy
Behavioral: Cognitive behavior therapy (CBT)
Participants will complete worksheets and group discussion on how to increase positive mood and activity.
Active Comparator: 2
Participants will receive supportive/expressive therapy
Behavioral: Supportive/expressive (S/E) therapy
Participants will be encouraged to express feelings and emotions without advice giving.
Active Comparator: 3
Participants will receive bibliotherapy
Participants will be given a book on how to increase their mood.
No Intervention: 4
Participants in the control condition will receive no treatment
- Depressive symptoms [ Time Frame: Measured at Year 1 ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00183417
|United States, Texas|
|University of Texas at Austin|
|Austin, Texas, United States, 78712|
|Principal Investigator:||Eric M. Stice, PhD||University of Texas at Austin|