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An Open Clinical Trial to Assess the Influence of Newly Prescribed Aminobiphosphonates on Arterial Stiffness

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ClinicalTrials.gov Identifier: NCT00180232
Recruitment Status : Withdrawn (Clinical partner left University,)
First Posted : September 16, 2005
Last Update Posted : February 3, 2012
Sponsor:
Information provided by:
Technische Universität Dresden

Brief Summary:
The study tries to reveal if aminobisphosphonates influence aside the bone density also the vascular status in the typical elderly patient population

Condition or disease
Arteriosclerosis Osteoporosis

Detailed Description:
The subjects - starting bisphosphonate treatment due to medical reasons - will be additionally investigated as outpatients (arterial stiffness, applanation tonometry), for each subject 3 individual dates with a duration of approx. 30 min each are scheduled, prior to therapy with bisphosphonate, after 3 and 6 month of treatment

Study Type : Observational
Actual Enrollment : 0 participants
Time Perspective: Prospective
Official Title: An Open Clinical Trial to Assess the Influence of Newly Prescribed Aminobiphosphonates on Arterial Stiffness (Changes of the Aortal Elasticity Due to a Newly Established Aminobiphosphinate Therapy for the Treatment of Osteoporosis)
Study Start Date : April 2006
Study Completion Date : June 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Osteoporosis
U.S. FDA Resources

Group/Cohort
1
Patients starting an aminobisphosphonate therapy due to medical reasons Broca-index: between -20 and +25% who are willing and capable to confirm written consent to enrolment after ample information has been provided




Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients starting an aminobisphosphonate therapy due to medical reasons Broca-index: between -20 and +25%
Criteria

Inclusion Criteria:

  • Patients starting an aminobisphosphonate therapy due to medical reasons Broca-index: between -20 and +25% who are willing and capable to confirm written consent to enrolment after ample information has been provided

Exclusion Criteria:

  • patients with major cardiovascular disease patients participating in another clinical trial 1month prior to inclusion in this study patients unable or unwilling to give informed consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00180232


Locations
Germany
Medizinische Fakultät der Technischen Universität Dresden
Dresden, Germany, 01307
Sponsors and Collaborators
Technische Universität Dresden
Investigators
Principal Investigator: Joachim Siegert, MDDPharm,Phd Technische Universität Dresden

ClinicalTrials.gov Identifier: NCT00180232     History of Changes
Other Study ID Numbers: EK160082004
First Posted: September 16, 2005    Key Record Dates
Last Update Posted: February 3, 2012
Last Verified: February 2012

Additional relevant MeSH terms:
Osteoporosis
Arteriosclerosis
Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases
Metabolic Diseases
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases