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Tumor Hypoxia of Head-and-neck Cancer Underwent Radiation Therapy Measured With F-18-FMISO

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Jörg Kotzerke, Technische Universität Dresden Identifier:
First received: September 13, 2005
Last updated: March 15, 2016
Last verified: March 2016
The purpose of this study is to describe the regional and global tumor hypoxia in head-and-neck cancer during percutaneous radiation therapy

Condition Phase
Head and Neck Neoplasms
Phase 2

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Tumor Hypoxia of Head-and-neck Cancer Underwent Radiation Therapy Measured With F-18-FMISO

Resource links provided by NLM:

Further study details as provided by Technische Universität Dresden:

Enrollment: 60
Study Start Date: July 2006
Estimated Study Completion Date: August 2018
Estimated Primary Completion Date: August 2018 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The study includes consecutive patients from the Department of Radiooncology with head and neck cancer (HNC) intended for a curative chemoradiotherapy.

Inclusion Criteria:

  • histologically confirmed head-and-neck cancer not curable by surgery
  • Karnofsky > 70%
  • tumor volume and localisation allow curative radiotherapy
  • written consent

Exclusion Criteria:

  • metastases
  • earlier radiation therapy of head and neck
  • pregnancy
  • secondary malignancy excluding dermal carcinoma and Tis-carcinoma of cervix uteri
  • psychiatric impairment
  Contacts and Locations
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Please refer to this study by its identifier: NCT00180180

Department of Nuclear Medicine
Dresden, Germany, 01307
Sponsors and Collaborators
Technische Universität Dresden
Principal Investigator: Joerg Kotzerke, MD Department of Nuclear Medicine
  More Information

Responsible Party: Jörg Kotzerke, Prof. Dr., Technische Universität Dresden Identifier: NCT00180180     History of Changes
Other Study ID Numbers: HNO-FMISO-FU
Study First Received: September 13, 2005
Last Updated: March 15, 2016

Keywords provided by Technische Universität Dresden:
head-and-neck cancer
radiation therapy

Additional relevant MeSH terms:
Head and Neck Neoplasms
Neoplasms by Site
Neoplasms processed this record on May 24, 2017