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Repository: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00179075
First Posted: September 15, 2005
Last Update Posted: December 15, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Vanderbilt University
  Purpose
This is a repository to store blood and stem cell samples for future research.

Condition
Hematopoietic Stem Cell Transplantation Graft vs Host Disease

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Repository for Study: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant (HSCT)

Resource links provided by NLM:


Further study details as provided by Vanderbilt University:

Estimated Enrollment: 100
Study Start Date: April 2003
Study Completion Date: April 2008
Detailed Description:
Our Hypothesis is that the graft-versus-tumor effect can be enhanced while minimizing the complications of GVHD by determining the qualitative and quantitative changes in T regulatory cells throughout the transplant process. Our understanding of this can lead to new treatment strategies and improved clinical therapeutic implications.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients 18-70 years old undergoing either autologous transplant or allogeneic transplant for various hematologic conditions
Criteria

Inclusion Criteria:

  • Patients 18-70 years old undergoing either autologous transplant or allogeneic transplant for various hematologic conditions

Exclusion Criteria:

  • Patients < 18 or > 70 years old undergoing either autologous transplant or allogeneic transplant
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00179075


Locations
United States, Tennessee
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232
Sponsors and Collaborators
Vanderbilt University
Investigators
Principal Investigator: Adetola A Kassim, MD Vanderbilt University Medical Center
  More Information

Responsible Party: Adetola A. Kassim, MD, Vanderbilt University
ClinicalTrials.gov Identifier: NCT00179075     History of Changes
Other Study ID Numbers: BMT 030263
First Submitted: September 13, 2005
First Posted: September 15, 2005
Last Update Posted: December 15, 2008
Last Verified: December 2008

Keywords provided by Vanderbilt University:
T-Lymphocyte Subsets

Additional relevant MeSH terms:
Graft vs Host Disease
Immune System Diseases