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Radiation Dosimetry in Teeth

This study has been terminated.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00178347
First Posted: September 15, 2005
Last Update Posted: May 19, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Rochester
  Purpose

Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure. The specific type of modification also depends to some extent upon the type of tissue irradiated. It has been shown that it is possible to read the tooth enamel irradiation record using techniques such as electron paramagnetic resonance (EPR), or electron spin resonance (ESR).

It is proposed to examine radiation responses in approximately one hundred (100) human teeth. This would include teeth free of, as well as those containing, amalgam (silver) restorations. For the first group, teeth that have already been collected (pre-existing pathological specimens) would be used. These teeth were surgical/pathological discards collected without identifiers by the dental providers.


Condition Intervention
Radiation Tolerance Radiation: Exposure to irradiation

Study Type: Observational
Study Design: Time Perspective: Retrospective
Official Title: Radiation Dosimetry in Teeth

Further study details as provided by University of Rochester:

Estimated Enrollment: 10
Study Start Date: December 2004
Intervention Details:
    Radiation: Exposure to irradiation
    Treatment for Cancer using Radiation -dose will be the standard of Care for the type of Cancer being treated
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
discarded pathological specimen(teeth)
Criteria

Inclusion Criteria:

  • Discarded pathologic specimens (teeth)
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00178347


Locations
United States, New York
University of Rochester, Dept. Radiation Oncology
Rochester, New York, United States, 14642
Sponsors and Collaborators
University of Rochester
Investigators
Study Chair: Paul Okunieff, MD University of Rochester, Dept. of Radiation Oncology
  More Information

Responsible Party: Paul Okunieff, University of Rochester, Medical Center
ClinicalTrials.gov Identifier: NCT00178347     History of Changes
Other Study ID Numbers: URCC 11070
First Submitted: September 12, 2005
First Posted: September 15, 2005
Last Update Posted: May 19, 2009
Last Verified: May 2009