Radiation Dosimetry in Teeth
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00178347|
Recruitment Status : Terminated
First Posted : September 15, 2005
Last Update Posted : May 19, 2009
Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure. The specific type of modification also depends to some extent upon the type of tissue irradiated. It has been shown that it is possible to read the tooth enamel irradiation record using techniques such as electron paramagnetic resonance (EPR), or electron spin resonance (ESR).
It is proposed to examine radiation responses in approximately one hundred (100) human teeth. This would include teeth free of, as well as those containing, amalgam (silver) restorations. For the first group, teeth that have already been collected (pre-existing pathological specimens) would be used. These teeth were surgical/pathological discards collected without identifiers by the dental providers.
|Condition or disease||Intervention/treatment|
|Radiation Tolerance||Radiation: Exposure to irradiation|
|Study Type :||Observational|
|Estimated Enrollment :||10 participants|
|Official Title:||Radiation Dosimetry in Teeth|
|Study Start Date :||December 2004|
Radiation: Exposure to irradiation
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00178347
|United States, New York|
|University of Rochester, Dept. Radiation Oncology|
|Rochester, New York, United States, 14642|
|Study Chair:||Paul Okunieff, MD||University of Rochester, Dept. of Radiation Oncology|