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Measuring Alterations of DNA in Human Blood

This study has been completed.
Litron Laboratories
Information provided by:
University of Rochester Identifier:
First received: September 12, 2005
Last updated: September 6, 2006
Last verified: September 2006
The purpose of this research is to evaluate an automated, laser-based technique for measuring DNA damge resulting from radiation. We want to use controlled exposure on cancer patients to help develop a measurement to test people who may have been accidentally exposed to radiation.


Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective

Further study details as provided by University of Rochester:

Estimated Enrollment: 24

Ages Eligible for Study:   21 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Male or female, age 21 to 70 years old.
  • Patient undergoing with anti-neoplastic agent(s) known to have genotoxic activity (e.g., cyclophosphamide, 5-FU, cisplatin, Ara-C.
  • X-irradiation may be considered, so long as a substantial fraction of red marrow is exposed (e.g., femur or chest/trunk region);
  • treatment could be ongoing therapy or initial therapy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00178308

United States, New York
University of Rochester
Rochester, New York, United States
Sponsors and Collaborators
University of Rochester
Litron Laboratories
Principal Investigator: Yuhchyau Chen, MD, Ph.D Universtiy of Rochester, Dept of Radiation Oncology
  More Information Identifier: NCT00178308     History of Changes
Other Study ID Numbers: URCC 1702
Study First Received: September 12, 2005
Last Updated: September 6, 2006 processed this record on September 18, 2017