Coordinating Center for Caregiver Intervention Trial
The primary goal of this study is to test a single multi-component intervention among family caregivers of persons with Alzheimer’s disease or related disorders. The overall objectives of study are to 1) identify and reduce modifiable risk factors among diverse family caregivers of patients with Alzheimer’s Disease or a related disorder, 2) enhance the quality of care of the care recipients, and 3) enhance the well-being of the caregivers.
Procedure: multicomponent psychosocial intervention
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Coordinating Center for Multisite Intervention Trial for Diverse Caregivers|
- multivariate quality of life indicator- assessed caregiver burden, depressive symptoms, self-care, social support and patient problem behaviors. Assessed at six months post-randomization.
- Caregiver clinical depression and patient institutional placement-six months post-randomization.
|Study Start Date:||June 2002|
|Estimated Study Completion Date:||August 2004|
The proposed Coordinating Center (CC) will work with five sites and staff from the National Institute on Aging (NIA) and the National Institute of Nursing Research (NINR) to implement a multi-site caregiver intervention trial. The overall objective of this research program is to refine and test a multicomponent psychosocial intervention to reduce burden and depression among family caregivers of persons with Alzheimer's Disease or a related disorder. This competing renewal will build upon results obtained from its parent multi-site feasibility study, Resources for Enhancing Alzheimer’s Caregiver Health (REACH) funded by the NIA/NINR as a cooperative agreement (UO1-AG13305). In the study proposed here, five intervention sites (Birmingham, Memphis, Miami, Palo Alto, and Philadelphia) will recruit 600 (120 per site) caregiver-care recipient dyads consisting of equal numbers of African Americans/Blacks, Hispanics/Latinos, and Caucasians/Whites. Caregivers will be randomized to either an in-home multicomponent intervention condition or a standardized information-only control condition.
The Coordinating Center at the University of Pittsburgh will work with the intervention site investigators and the NIA/NINR to support the implementation of the intervention study at each site and to collect and analyze a common database across sites.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00177489
|United States, Alabama|
|University of Alabama at Birmingham|
|Birmingham, Alabama, United States, 35294-2041|
|United States, California|
|Stanford University and Veterans Affairs|
|Menlo Park, California, United States, 94025|
|United States, Florida|
|University of Miami at Miami, Center on Adult Development and Aging|
|Miami, Florida, United States, 33136|
|United States, Pennsylvania|
|Thomas Jefferson University at Philadelphia, Center for Applied Research on Aging and Health|
|Philadelphia, Pennsylvania, United States, 19107|
|United States, Tennessee|
|University of Tennessee Health Science Center|
|Memphis, Tennessee, United States, 38163|
|Principal Investigator:||Richard Schulz, Ph.D.||Professor of Psychiatry and Director, University Center for Social and Urban Research, University of Pittsburgh|