Dextromethorphan in Treating Patients With Fatigue Caused by Cancer
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|ClinicalTrials.gov Identifier: NCT00176540|
Recruitment Status : Terminated (slow accrual)
First Posted : September 15, 2005
Last Update Posted : May 17, 2011
RATIONALE: Dextromethorphan may help relieve fatigue in patients with cancer.
PURPOSE: This clinical trial is studying how well dextromethorphan works in treating patients with fatigue caused by cancer.
|Condition or disease||Intervention/treatment||Phase|
|Fatigue Unspecified Adult Solid Tumor, Protocol Specific Unspecified Childhood Solid Tumor, Protocol Specific||Drug: dextromethorphan hydrobromide||Not Applicable|
- Assess the effects of dextromethorphan hydrobromide in patients with cancer-related fatigue.
- Correlate the changes in cancer-related fatigue with the levels of plasma homocysteine versus red blood cell folate.
OUTLINE: This is a multicenter, open-label, pilot study.
Patients receive oral dextromethorphan hydrobromide 3 times a day on days 1-7. Treatment repeats weekly for up to 3 weeks in the absence of disease progression or unacceptable toxicity.
PROJECTED ACCRUAL: A total of 30 patients will be accrued for this study.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||30 participants|
|Masking:||None (Open Label)|
|Primary Purpose:||Supportive Care|
|Official Title:||A Pilot Trial to Evaluate the Effects of Dextromethorphan in Patients Suffering From Cancer-Related Fatigue|
|Study Start Date :||October 2003|
|Actual Primary Completion Date :||August 2007|
|Actual Study Completion Date :||August 2007|
- Correlation of the changes in cancer-related fatigue with the levels of plasma homocysteine versus red blood cell folate
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00176540
|United States, New Jersey|
|Cancer Institute of New Jersey at Hamilton|
|Hamilton, New Jersey, United States, 08690|
|Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School|
|New Brunswick, New Jersey, United States, 08903|
|Principal Investigator:||Susan Goodin, PharmD, FCCP, BCOP||Rutgers Cancer Institute of New Jersey|