We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Risk Indicators in Patients With Ventricular Fibrillation During Acute Myocardial Infarction

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2005 by Heidelberg University.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00175942
First Posted: September 15, 2005
Last Update Posted: September 15, 2005
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Heidelberg University
  Purpose
Sudden cardiac death is in most cases triggered by ischemia-related ventricular tachyarrhythmias and accounts for 50% of deaths from cardiovascular disease in developed countries. Chronic elevation of indicators of coagulation activation has been found in patients with coronary heart disease , but a role of coagulation activation and proinflammatory state as a potential risk factor for ventricular fibrillation (VF) during acute myocardial infarction has not been investigated.

Condition
Acute Myocardial Infarction Sudden Cardiac Death

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Retrospective/Prospective
Official Title: Indicators of Coagulation Activation and Inflammation Contributing to Ventricular Fibrillation Complicating Acute Myocardial Infarction

Resource links provided by NLM:


Further study details as provided by Heidelberg University:

Estimated Enrollment: 300
Study Start Date: February 2003
Detailed Description:
Sudden cardiac death (SCD) is in most cases triggered by ischemia-related ventricular arrhythmias and is responsible for 50% of the mortality from cardiovascular disease in developed countries (1). Chronic elevation of indicators of coagulation activation and inflammation has been found in patients with coronary heart disease and may contribute to vasculatory disorders probably contributing to the development of arrhythmogenesis. However, the role of coagulation activation as a potential risk factor for ventricular fibrillation during acute myocardial infarction has not been investigated yet.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

ST-elevation myocardial infarction ventricular fibrillation during acute MI

Exclusion Criteria:

NSTEMI coagulation disorders, e.g.intake of coumadin

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00175942


Contacts
Contact: Elif Elmas, MD, Dr. 00496213833988
Contact: Martina Brückmann, MD, Dr.

Locations
Germany
University Hospital of Mannheim, University of Heidelberg Recruiting
Mannheim, Germany, 68167
Sub-Investigator: Elif Elmas, MD. Dr         
Sponsors and Collaborators
Heidelberg University
Investigators
Principal Investigator: Carl E. Dempfle, Prof.Dr. University Hospital of Mannheim, University of Heidelberg
  More Information

ClinicalTrials.gov Identifier: NCT00175942     History of Changes
Other Study ID Numbers: 0229.3
First Submitted: September 10, 2005
First Posted: September 15, 2005
Last Update Posted: September 15, 2005
Last Verified: May 2005

Keywords provided by Heidelberg University:
acute myocardial infarction
ventricular fibrillation
coagulation
inflammation

Additional relevant MeSH terms:
Infarction
Myocardial Infarction
Death
Death, Sudden, Cardiac
Ventricular Fibrillation
Ischemia
Pathologic Processes
Necrosis
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases
Heart Arrest
Death, Sudden
Arrhythmias, Cardiac