Magnetic Resonance Imaging in Subjects With Gouty Tophi
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|ClinicalTrials.gov Identifier: NCT00174954|
Recruitment Status : Completed
First Posted : September 15, 2005
Results First Posted : July 16, 2009
Last Update Posted : July 27, 2010
|Condition or disease||Intervention/treatment||Phase|
|Hyperuricemia Gout||Procedure: MRI||Phase 2|
|Study Type :||Observational|
|Actual Enrollment :||32 participants|
|Official Title:||A Study to Validate Magnetic Resonance Imaging (MRI) in the Quantitative Assessment of Gouty Tophi.|
|Study Start Date :||March 2002|
|Primary Completion Date :||January 2003|
|Study Completion Date :||January 2003|
Volumes/measurements of tophi determined by serial MRIs
Subjects underwent MRI to evaluate tophi.
- Measurement of Tophi by MRI - Difference in Volument Between Visits [ Time Frame: Visit 1 (Day 1) and Visit 2 (Days 6-11) ]Two independent readers determined volume of the same tophus by MRI at 2 separate visits scheduled no more than 10 days apart. Difference in volume between Visit 1 and 2 for the same tophus was pooled across readers.
- Measurement of Tophi by MRI - Difference in Volume Between Readers [ Time Frame: Visit 1 (Day 1) and Visit 2 (Days 6-11) ]Two independent readers determined volume of the same tophus by MRI at 2 separate visits scheduled no more than 10 days apart. Difference in Reader 2 volume and Reader 1 volume for the same tophus were pooled across visits.
Biospecimen Retention: None Retained
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00174954
|Study Chair:||Medical Director||Takeda|