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Sensorimotor Dysfunction of Individuals With Neck Pain

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2004 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Information provided by:
National Taiwan University Hospital Identifier:
First received: September 13, 2005
Last updated: December 20, 2005
Last verified: December 2004
Systematically assessing the proprioception-coordination capacity of the spine in patients with different severity of neck disability could reveal how the dysfunction of the sensory-motor system was progressed. From the result of the research, a prospective study would be designed to test the hypotheses that described the mechanism of neck pain based on the results to the present study.

Condition Phase
Posterior Neck Pain Phase 1

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: Sensorimotor Dysfunction of Individuals With Neck Pain

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 60
Study Start Date: July 2005
Estimated Study Completion Date: July 2006
Detailed Description:

The purposes of this research were to investigate the effect of age and chronic neck pain on cervical proprioception, the change of ultrasonographic (USD) patterns in deep neck muscle and superficial neck muscles. The hypotheses of this research included: 1) the alteration of neck proprioception is determined predominantly by the changed activation deep neck muscles and superficial neck muscles. 2) Age factor contributes to the alteration of cervicocephalic sensibility, USD pattern of deep and superficial muscles. 3) Chronic pain contributes to the alteration of cervicocephalic sensibility, USD pattern of deep and superficial muscles.

Neck proprioception is measured by an ultrasound-based coordinate measuring system (CMS 70P, Zebris, Germany) by asking the subjects to performed head repositioning to the neutral head position or to a target position in three cardinal plane. These repositioning error expressed in root mean square errors could represent the craniocervical kinesthetic sensibility. The change of muscle thickness (mm) of the superficial (Trapezium, Splenius) and deep (semispinalis cervicis and multifidus) dorsal neck muscle is measured by a real-time ultrasonographic scanner (HDI 5000, ATL Ultrasound, USA). Image is obtained for each cervical level, and the thickness of the muscle is identified manually using a custom-written C++ computer graphic program. The measurements of pain intensity and pain frequency are modified from the symptoms questionnaire to indicate the intensity, location, frequency and duration of pain and disability of the subjects. The age and pain effects for each independent variables measured in patients with chronic neck pain (pain: intensity, location, frequency, and duration, NDI), will be tested with the General Linear Model (GLM; age and pain factors). The confounding factors such as gender, range of motion, body height and weight are controlled in the regression model.


Ages Eligible for Study:   20 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • posterior neck pain with duration over 3 months

Exclusion Criteria:

  • surgery on cervical spine
  • achilosing spondylitis
  • diabetes mellitus
  • traumatic injury directly over head and neck area
  • progressing neurological disease
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00174148

Contact: Shwu-Fen Wang, PT Phd 886-2-23123456 ext 7558

School and Graduate Institution of Physical Therapy, College of Medicine,Nnational Taiwan University Recruiting
Taipei, Taiwan
Contact: Shwu-Fen Wang, PT, Phd    886-2-23123456 ext 7558   
Sponsors and Collaborators
National Taiwan University Hospital
Study Chair: Shwu-fen Wang, PT Phd National Taiwan University Hospital
  More Information Identifier: NCT00174148     History of Changes
Other Study ID Numbers: 9361701250
Study First Received: September 13, 2005
Last Updated: December 20, 2005

Additional relevant MeSH terms:
Neck Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms processed this record on September 21, 2017