Sarcopenia Studies for the Elderly Population in Taiwan

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00174135
Recruitment Status : Unknown
Verified December 2004 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : September 15, 2005
Last Update Posted : August 30, 2007
Information provided by:
National Taiwan University Hospital

Brief Summary:
Health promotion in the elderly has been a major recent public health concern. Sarcopenia is a term utilized to define the loss of muscle mass and strength that occurs with aging. It has been demonstrated to be associated with decreased functional capacity among the elderly. The magnitude of the public health problem posed by sarcopenia is not yet established. The purposes of this study are to investigate sarcopenia and its relationship with functional status in elderly Taiwanese community-dwellers, and to develop the preventive strategy for sarcopenia in the elderly. Firstly, the investigators will recruit 100 volunteers (aged 18-90 years old) to participate in this study. All of the participants will receive bioelectric impedance analysis (BIA), muscle strength and endurance assessment, physical activity level assessment by a seven-day recall questionnaire, protein intake assessment, cognition evaluation (Mini-Mental State Examination) and functional status assessment by the Functional Independence Measurement (FIM) questionnaire. A multiple regression model will be used for statistical analyses. Then, this project will be used to evaluate the efficacy of a 12-week supervised resistance strengthening exercise program for sarcopenia in the elderly. Participants who are defined as having sarcopenia from the previous examination will be randomized into either the exercise or control groups. Subjects in the exercise group will receive resistance strengthening exercises 3 times per week for 12 weeks. All measurements will be performed as described above. The investigators expect that resistance exercises are effective in offsetting age-related decline of muscle mass and strength in the elderly.

Condition or disease

Study Type : Observational
Estimated Enrollment : 100 participants
Time Perspective: Cross-Sectional
Time Perspective: Retrospective/Prospective
Official Title: Sarcopenia Studies for the Elderly Population in Taiwan
Study Start Date : August 2005

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • 18-90 year old healthy adults

Exclusion Criteria:

  • No systemic diseases

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00174135

Contact: Meng-Yueh Chien, MS 886-2-23123456 ext 7559

National Taiwan University Hospital Recruiting
Taipei, Taiwan
Contact: Meng-Yueh Chien    886-2-23123456 ext 7559   
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Meng-Yueh Chien, MS National Taiwan University, College of Medicine

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00174135     History of Changes
Other Study ID Numbers: 9361701210
First Posted: September 15, 2005    Key Record Dates
Last Update Posted: August 30, 2007
Last Verified: December 2004

Keywords provided by National Taiwan University Hospital:

Additional relevant MeSH terms:
Muscular Atrophy
Neuromuscular Manifestations
Neurologic Manifestations
Nervous System Diseases
Pathological Conditions, Anatomical
Signs and Symptoms