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Clinical Study of SARS in Children

This study has been completed.
National Science Council, Taiwan
Information provided by:
National Taiwan University Hospital Identifier:
First received: September 12, 2005
Last updated: October 26, 2005
Last verified: August 2005
Severe acute Respiratory Syndrome (SARS) is an emerging infectious disease. It is caused by a novel SARS-associated coronavirus. According to the epidemiological data, it is highly infectious by intimate contact, respiratory secretion, or direct contact with infectious body fluid. By June 1, 2003, Center for Disease Control Taiwan, R.O.C reported 677 probable SARS cases. Among them, 93.2% (631/677) were more than 20 years old. Only 6.8% (46/677) were under 20 years old. Usually the major hosts of respiratory viruses are children, but evidence up to now shows that SARS is mainly a disease of adults. The data of clinical presentation and epidemiological prevalence in teenage group and children are lacking. Therefore, this project is aimed at the children and teenager among 1 month to eighteen years old. Seroepidemiology of SARS-CoV infection in children would be investigated. Patients who admitted to pediatric wards or visited ER and received blood sampling due to the need of clinical diagnosis/management would be enrolled. After the necessary laboratory examinations were done, the remaining serum would be collected and tested for anti-SARS-CoV IgG by ELISA.


Study Type: Observational
Study Design: Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Retrospective/Prospective
Official Title: Clinical Study of SARS in Children

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 800
Study Start Date: April 2003
Estimated Study Completion Date: March 2005

Ages Eligible for Study:   1 Month to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients aged from 1 month to 18 years old
  • Received blood sampling during admission or at emergency department due to the need of clinical diagnosis/management

Exclusion Criteria:

  Contacts and Locations
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Please refer to this study by its identifier: NCT00173576

Sponsors and Collaborators
National Taiwan University Hospital
National Science Council, Taiwan
Principal Investigator: Li-Min Huang, MD, PhD Department of Pediatrics, College of Medicine, National Taiwan University and Graduate Institute of Preventive Medicine, College of Public Health, National Taiwan University
  More Information Identifier: NCT00173576     History of Changes
Other Study ID Numbers: 9461700732
Study First Received: September 12, 2005
Last Updated: October 26, 2005 processed this record on August 22, 2017