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Trial record 16 of 29 for:    "Turner Syndrome" | "Estrogens"

Perception and Attitude Toward Estrogen Therapy Among Surgically Menopausal Women

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00173550
Recruitment Status : Unknown
Verified July 2005 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : September 15, 2005
Last Update Posted : January 23, 2007
National Science Council, Taiwan
Information provided by:
National Taiwan University Hospital

Brief Summary:
The aim of this study is to survey patient’s cognition and attitude about health-related quality of life, use of estrogen, experience of menopausal syndrome, compliance of medication, experience, and satisfaction for women who underwent hysterectomy and bilateral oophorectomy before menopause.

Condition or disease Intervention/treatment
Menopause, Premature Hysterectomy Ovariectomy Estrogen Replacement Therapy Attitude Perception Procedure: Hysterectomy and Bilateral salpingo-oophorectomy

Detailed Description:
The cognition and attitude of menopausal women toward hormone replacement could have been changed since the report from WHI in July 2002. Previously, many women used hormone replacement to prevent cardiovascular disease and osteoporosis. Recently, the use has been challenged, exaggerated, and also discussed both in media press and academic meetings. Many women dare not to use them. The women who underwent hysterectomy and bilateral salpingo-oophorectomy before menopause may immediately face the problems caused by deficiency of female sex hormone. For this group of women, as yet there is no conclusion about whether the women should take hormone replacement therapy for a long time to osteoporosis, cardiovascular disease and other chronic disease. The arm for this study from WHI is not closed yet. While the women in our area might have been influenced by this report and have changed their mind. It is essential for us to make a clear understanding about the cognition and attitude for hormone replacement therapy for women who underwent hysterectomy and bilateral salpingo- oophorectomy. Therefore, it may be a pioneer study and worthwhile to do this study. Data from a medical center from 2000 to 2004 will be examined for evidence of bilateral oophorectomy & hysterectomy. The cause for the surgery will be confirmed by pathological findings. These women who were under 50 years of age will be candidate of the study. The women will be interviewed about their beliefs, and cognition, regarding their quality of life and health risks as well as their opinion on menopause and hormone replacement therapy.

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Study Type : Observational
Enrollment : 200 participants
Observational Model: Defined Population
Time Perspective: Cross-Sectional
Time Perspective: Retrospective
Official Title: Perception and Attitude Toward Estrogen Therapy Among Operated Women With Premature or Immature Menopause
Study Start Date : August 2004

Resource links provided by the National Library of Medicine

Drug Information available for: Estrogens

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Age under 50
  • Hysterectomy and bilateral oophorectomy

Exclusion Criteria:

  • Unwilling to answer the questionnaires

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00173550

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Contact: Ruey-Jien Chen, MD, PhD 886-2-23123456 ext 5158

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National Taiwan University Hospital Department of Obstetrics and Gynecology Recruiting
Taipei, Taiwan, 100
Contact: Ruey-Jien Chen, MD, PhD    886-2-2312-3456 ext 5158   
Principal Investigator: Ruey-Jien Chen, MD, PhD         
Sponsors and Collaborators
National Taiwan University Hospital
National Science Council, Taiwan
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Principal Investigator: Ruey-Jien Chen, MD, PhD Department or Obstetrics and Gynecology, National Taiwan university Hospital

Additional Information:
Layout table for additonal information Identifier: NCT00173550     History of Changes
Other Study ID Numbers: 9461700710
First Posted: September 15, 2005    Key Record Dates
Last Update Posted: January 23, 2007
Last Verified: July 2005

Keywords provided by National Taiwan University Hospital:
Menopause, premature
Estrogen Replacement Therapy

Additional relevant MeSH terms:
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Primary Ovarian Insufficiency
Premature Birth
Menopause, Premature
Obstetric Labor, Premature
Obstetric Labor Complications
Pregnancy Complications
Ovarian Diseases
Adnexal Diseases
Genital Diseases, Female
Gonadal Disorders
Endocrine System Diseases
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs