The Difference in Presentation Level of Variant Receptors in Female Breast Tissue in Macromastia and Micromastia
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00173251 |
Recruitment Status
: Unknown
Verified June 2005 by National Taiwan University Hospital.
Recruitment status was: Not yet recruiting
First Posted
: September 15, 2005
Last Update Posted
: September 15, 2005
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Aging | Procedure: obtain surgical specimen for analysis | Phase 1 |
Large breasts cause neck and back pain, irritating grooves, cut in the skin of the shoulders by the pressure of brassiere straps, breast pain, and maceration and dermatoses in the inframammary region. From a psychological point of view, excessively large breasts can be troublesome focus of embarrassment for the teenager as well as the woman in her senior years. Unilateral hypertrophy with asymmetry heightens embarrassment. Thus, patients seek to reduce the size of their breasts.
In the human female, variant receptors were detected in epithelial cells in normal breast tissue, benign breast lesions, breast carcinoma tissue, and breast cancer cell lines2-11. The cause of the difference in breast development status is still unclear. Abnormalities at the tissue receptor level may be important in the pathophysiology of macromastia. This study aimed to make clear the difference in variant receptor levels between breast hypertrophy patients and macromastia ones by examining the receptor levels in breast tissue. Then, we could explore the possible etiology of mammary hypertrophy and macromastia.
Study Type : | Interventional (Clinical Trial) |
Enrollment : | 60 participants |
Allocation: | Non-Randomized |
Intervention Model: | Single Group Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Educational/Counseling/Training |
Study Start Date : | January 2006 |
Study Completion Date : | August 2006 |
- difference in receptor expression level

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 20 Years to 80 Years (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- patients receiving reduction mammoplasty
Exclusion Criteria:

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00173251
Contact: Hao-Chih Tai, M.D. | 886-2-23123456 ext 5109 | phoebe@ha.mc.ntu.edu.tw |
Principal Investigator: | Hao-Chih Tai, M.D. | National Taiwan University Hospital |
ClinicalTrials.gov Identifier: | NCT00173251 History of Changes |
Other Study ID Numbers: |
9461700605 |
First Posted: | September 15, 2005 Key Record Dates |
Last Update Posted: | September 15, 2005 |
Last Verified: | June 2005 |