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Effect of Cyclic Tensional Force on Osteogenic Differentiation of Human Periodontal Ligament Stem Cells

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2005 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Information provided by:
National Taiwan University Hospital Identifier:
First received: September 12, 2005
Last updated: October 10, 2007
Last verified: March 2005
The purpose of this study is to observe cyclic tensional force on the osteogenic differentiation of human periodontal ligament stem cells.


Study Type: Observational
Study Design: Time Perspective: Prospective

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 20
Study Start Date: April 2005
Estimated Study Completion Date: July 2006
Detailed Description:
This study is to investigate the effect of the cyclic mechanical strain on the osteogenic differentiation of mesenchymal stem cells. Mesenchymal stem cells will be cultured from the periodontal ligament tissue of the premolars extracted due to orthodontic reason.

Ages Eligible for Study:   13 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Orthodontic patients who need to have premolars extracted
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00172744

School of Dentistry, College of Medicine, National Taiwan University
Taipei, Taiwan
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Yi-Jane Chen, MSD School of Dentistry, College of Medicine, National Taiwan University
  More Information Identifier: NCT00172744     History of Changes
Other Study ID Numbers: 9361701291 
Study First Received: September 12, 2005
Last Updated: October 10, 2007

Keywords provided by National Taiwan University Hospital:
stem cells
periodontal cells
mechanical stress
periodontal ligament processed this record on February 20, 2017