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The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance

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ClinicalTrials.gov Identifier: NCT00172614
Recruitment Status : Unknown
Verified December 2004 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : September 15, 2005
Last Update Posted : March 29, 2006
Sponsor:
Information provided by:
National Taiwan University Hospital

Brief Summary:
Insulin resistance and disturbances in energy homeostasis are associated with body weight changes, such as diabetes, hypertension, hyperlipidemia, obesity, cancer cachexia, aging, and acute or chronic infectious diseases. Cytokines secreted by adipose tissue and inflammatory cells play important roles in the pathological conditions. Several novel cytokines were disclosed recently, but their functions have not been well known. Further investigation of these cytokines, resulting in insulin resistance and energy homeostasis, is very important to elucidate the mechanisms and develop new therapeutic strategies.

Condition or disease
Metabolic Syndrome X Cachexia Insulin Resistance

Detailed Description:
We are studying patients with body weight change, increased or decreased. Healthy people are the control group. We are recording body weight, body height, and physical exam results. In addition, we are drawing peripheral blood for further biochemical and cytokine assays.

Study Type : Observational
Estimated Enrollment : 300 participants
Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Study Start Date : December 2004

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U.S. FDA Resources





Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Insulin resistance condition

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00172614


Contacts
Contact: Jaw-Shiun Tsai, MD 886-2-23123456 ext 5349 jstsai@ha.mc.ntu.edu.tw

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan
Contact: Jaw-Shiun Tsai, MD         
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: Jaw-Shiun Tsai, MD National Taiwan University Hospital

ClinicalTrials.gov Identifier: NCT00172614     History of Changes
Other Study ID Numbers: 9361701201
First Posted: September 15, 2005    Key Record Dates
Last Update Posted: March 29, 2006
Last Verified: December 2004

Keywords provided by National Taiwan University Hospital:
metabolic syndrome

Additional relevant MeSH terms:
Metabolic Syndrome X
Insulin Resistance
Cachexia
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases
Emaciation
Weight Loss
Body Weight Changes
Body Weight
Signs and Symptoms