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The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2004 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00172614
First Posted: September 15, 2005
Last Update Posted: March 29, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Taiwan University Hospital
  Purpose
Insulin resistance and disturbances in energy homeostasis are associated with body weight changes, such as diabetes, hypertension, hyperlipidemia, obesity, cancer cachexia, aging, and acute or chronic infectious diseases. Cytokines secreted by adipose tissue and inflammatory cells play important roles in the pathological conditions. Several novel cytokines were disclosed recently, but their functions have not been well known. Further investigation of these cytokines, resulting in insulin resistance and energy homeostasis, is very important to elucidate the mechanisms and develop new therapeutic strategies.

Condition
Metabolic Syndrome X Cachexia Insulin Resistance

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 300
Study Start Date: December 2004
Detailed Description:
We are studying patients with body weight change, increased or decreased. Healthy people are the control group. We are recording body weight, body height, and physical exam results. In addition, we are drawing peripheral blood for further biochemical and cytokine assays.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Insulin resistance condition
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00172614


Contacts
Contact: Jaw-Shiun Tsai, MD 886-2-23123456 ext 5349 jstsai@ha.mc.ntu.edu.tw

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan
Contact: Jaw-Shiun Tsai, MD         
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: Jaw-Shiun Tsai, MD National Taiwan University Hospital
  More Information

ClinicalTrials.gov Identifier: NCT00172614     History of Changes
Other Study ID Numbers: 9361701201
First Submitted: September 12, 2005
First Posted: September 15, 2005
Last Update Posted: March 29, 2006
Last Verified: December 2004

Keywords provided by National Taiwan University Hospital:
metabolic syndrome

Additional relevant MeSH terms:
Metabolic Syndrome X
Insulin Resistance
Cachexia
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases
Emaciation
Weight Loss
Body Weight Changes
Body Weight
Signs and Symptoms