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Long Term Outcomes of EV71 CNS Infection

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2005 by National Taiwan University Hospital.
Recruitment status was  Recruiting
Information provided by:
National Taiwan University Hospital Identifier:
First received: September 12, 2005
Last updated: October 3, 2006
Last verified: June 2005
Our study involved 142 children with EV71 CNS infections that included 61 (43%) with viral meningitis, 53 (37%) with severe CNS involvement including encephalitis, polio-like syndrome and encephalomyelitis, and 28 (20%) with cardiopulmonary failure after CNS involvement. These children were subjected to physical and neurological examinations 2.85 (range 1.0-7.39) years after disease onset. Those below the age of 6 years took the Denver developmental screening test, while those 4 years and over took the intelligence quotient (IQ) test.

Central Nervous System Infection

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Retrospective/Prospective
Official Title: Long Term Outcomes of EV71 Central Nervous System Infection

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 150
Study Start Date: January 2003
Estimated Study Completion Date: May 2005
  Show Detailed Description


Ages Eligible for Study:   1 Month to 18 Years   (Child, Adult)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Virologically-confirmed EV71 cases with CNS involvement

Exclusion Criteria:

  • No evidence of EV71 infection
  • No evidence of CNS involvement
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00172393

Contact: Luan-Yin Chang, MD 886-2-23123456 ext 3245

National Taiwan University Hsopital Recruiting
Taipei, Taiwan, 100
Contact: Luan-Yin Chang, MD, PhD    886-2-23123456 ext 3245   
Principal Investigator: Luan-Yin Chang, MD, PhD         
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Luan-Yin Chang, MD, PhD National Taiwan University Hospital
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00172393     History of Changes
Other Study ID Numbers: 9311700446 
Study First Received: September 12, 2005
Last Updated: October 3, 2006
Health Authority: Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:

Additional relevant MeSH terms:
Communicable Diseases
Central Nervous System Infections
Central Nervous System Diseases
Nervous System Diseases processed this record on October 21, 2016