Pulmonary Rehabilitation in Interstitial Lung Disease
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00168285|
Recruitment Status : Unknown
Verified April 2007 by The Alfred.
Recruitment status was: Active, not recruiting
First Posted : September 15, 2005
Last Update Posted : April 5, 2007
Interstitial lung disease (ILD) is a highly disabling group of conditions including idiopathic pulmonary fibrosis (IPF), acute and chronic interstitial pneumonias, connective tissue diseases and sarcoidosis. People with ILD frequently experience breathlessness on exertion, which limits their ability to undertake daily activities. People with ILD report very poor quality of life due to low levels of physical functioning and vitality, and high levels of breathlessness and fatigue. There are few treatments for ILD and those that are available have limited impact on quality of life.
The aim of this study is to assess the effects of Pulmonary Rehabilitation, which consists of specialised exercise training for people with lung disease, on exercise capacity and quality of life in people with ILD. We hypothesis that exercise training will result in reduced dyspnoea, improved exercise tolerance and enhanced quality of life.
|Condition or disease||Intervention/treatment||Phase|
|Interstitial Lung Disease||Behavioral: Pulmonary Rehabilitation||Not Applicable|
Interstitial lung disease (ILD) is a highly disabling group of conditions including idiopathic pulmonary fibrosis (IPF), acute and chronic interstitial pneumonias, connective tissue diseases and sarcoidosis. People with ILD frequently experience breathlessness on exertion, which limits their ability to undertake daily activities and reduces health-related quality of life.Available treatments for ILD have proved largely ineffective, offering no improvement in survival and demonstrating only limited impact on quality of life.
Aims of the Research
- Evaluate the effects of Pulmonary Rehabilitation on exercise capacity and quality of life in patients with ILD
- Determine the physiological response to Pulmonary Rehabilitation in patients with ILD
- Determine the relationship between the aetiology and severity of ILD and the effects of Pulmonary Rehabilitation.
Comparisons: 8 weeks exercise training compared to control group (maximal exercise capacity, functional exercise capacity, dyspnoea, quality of life).
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||56 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Pulmonary Rehabilitation in Interstitial Lung Disease - a Multi-Centre, Single-Blinded Randomised Controlled Trial|
|Study Start Date :||March 2005|
|Estimated Study Completion Date :||May 2007|
U.S. FDA Resources
- Functional exercise capacity
- Maximal exercise capacity
- Health-related quality of life
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00168285
|Melbourne, Victoria, Australia, 3004|
|Melbourne, Victoria, Australia, 3084|
|Principal Investigator:||Anne E Holland, PhD||Alfred Hospital and LaTrobe University|
|Principal Investigator:||Matthew Conron, MBBS||The Alfred|
|Principal Investigator:||Prue Munro, BAppSc||The Alfred|
|Principal Investigator:||Christine McDonald, MBBS PhD||Austin Hospital, Melbourne Australia|
|Principal Investigator:||Catherine Hill, PhD||Austin Hospital, Melbourne Australia|